Author(s): Rim M. Harfouch, Manal Darwish, Wisam Al-Asadi, Ali F. Mohammad, Nour M. Gharib, Mohammad Haroun

Email(s): rimharfouch@au.edu.sy , rimharf@yahoo.com

DOI: 10.5958/0974-360X.2019.00576.6   

Address: Rim M. Harfouch1, Manal Darwish2, Wisam Al-Asadi2, Ali F. Mohammad3, Nour M. Gharib1, Mohammad Haroun3
1Department of Microbiology and Biochemistry, Faculty of Pharmacy, Al Andalus University, Tartous, Syria
2Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Al Andalus University, Tartous, Syria
3Department of Pharmaceutical Chemistry and Quality Control, Faculty of Pharmacy, Al Andalus University, Tartous, Syria
*Corresponding Author

Published In:   Volume - 12,      Issue - 7,     Year - 2019


ABSTRACT:
We aimed in this study to determine the antibacterial efficacy of essential oils of Rosmarinus officinalis, Salvia officinalis leaves and Anthemis nobilis flowers widespread in the Syrian coast against several strains of Staphylococcus aureus and Pseudomonas aeruginosa. The essential oils were extracted and the yield was measured using Clevenger apparatus. In vitro investigation of antibacterial activity using agar disc diffusion method and minimal inhibitory concentration (MIC) of each essential oil was determined by microdilution method against studied bacteria. Results demonstrated that Rosmarinus officinalis essential oil had the highest activity (MIC for Staphylococcus aureus was 3.9µl/ml and MIC for Pseudomonas aeruginosa was 7.8 µl/ml). Salvia officinalis essential oil had moderate antibacterial effect with MIC of 31.2 µl/ml and 125µl/ml against Staphylococcus aureus and Pseudomonas aeruginosa respectively. On the other hand, Anthemis nobilis essential oil had no efficacy against tested bacterial strains. According to our study, Rosmarinus officinalis essential oil exhibited higher antibacterial activity against both Staphylococcus aureus and Pseudomonas aeruginosa than this of Salvia officinalis.


Cite this article:
Rim M. Harfouch, Manal Darwish, Wisam Al-Asadi, Ali F. Mohammad, Nour M. Gharib, Mohammad Haroun. Antibacterial Activity of Essential Oils of Rosmarinus officinalis, Salvia officinalis and Anthemis nobilis Widespread in the Syrian Coast. Research J. Pharm. and Tech. 2019; 12(7):3410-3412. doi: 10.5958/0974-360X.2019.00576.6

Cite(Electronic):
Rim M. Harfouch, Manal Darwish, Wisam Al-Asadi, Ali F. Mohammad, Nour M. Gharib, Mohammad Haroun. Antibacterial Activity of Essential Oils of Rosmarinus officinalis, Salvia officinalis and Anthemis nobilis Widespread in the Syrian Coast. Research J. Pharm. and Tech. 2019; 12(7):3410-3412. doi: 10.5958/0974-360X.2019.00576.6   Available on: https://rjptonline.org/AbstractView.aspx?PID=2019-12-7-51


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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