Author(s): G. Chinna Devi, A. Eswar Kumar

Email(s): gchinnadevi@gmail.com

DOI: 10.5958/0974-360X.2019.00423.2   

Address: G. Chinna Devi*, A. Eswar Kumar
University College of Pharmaceutical Sciences, Palamuru University, Mahabubnagar, 509001, Telangana State
*Corresponding Author

Published In:   Volume - 12,      Issue - 5,     Year - 2019


ABSTRACT:
The natural toxic nature of chemotherapy drugs is essential for them to kill cancer cells, but it is also having the source of unfavourable side effects experienced by the patients. To reduce these side effects have to limit the healthy tissue exposure by encapsulating the drug. And the drug should be probable for rapid release inside the tumour. The microbubbles have an average size of less than that of red blood cells having 1–10 µm which are capable of penetrating even into the small blood capillaries and releasing drug and genes under the action of ultrasound field after reaching the specific area of interest. Micro bubbles dispersion method was introduced and investigated to develop oxygen transfer at low agitation rates and thus decreases power consumption and shear stress on the microorganisms. Microbubbles have been recently introduced as a promising drug delivery platform for ultrasound guided drug delivery. The micro bubbles may be targeted to specific tissue by incorporating protein ligands on the surface. This review focuses on the synthesis, characteristics of micro bubbles that give them beneficial properties and some important aspects of ultrasound parameters that are influence to enhance micro bubble mediated drug delivery.


Cite this article:
G. Chinna Devi, A. Eswar Kumar. Microbubbles-A Potential Novel Targeted Drug Delivery . Research J. Pharm. and Tech. 2019; 12(5):2511-2516. doi: 10.5958/0974-360X.2019.00423.2

Cite(Electronic):
G. Chinna Devi, A. Eswar Kumar. Microbubbles-A Potential Novel Targeted Drug Delivery . Research J. Pharm. and Tech. 2019; 12(5):2511-2516. doi: 10.5958/0974-360X.2019.00423.2   Available on: https://rjptonline.org/AbstractView.aspx?PID=2019-12-5-82


Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags


Not Available