Author(s): Karpagam P, G Manonmani, D Brindha

Email(s): Karpagam.psg@gmail.com

DOI: 10.5958/0974-360X.2019.00112.4   

Address: Karpagam P1*, G Manonmani2, D Brindha3
1Assistant Professor, Department of Costume Design and Fashion, PSG College of Arts and Science, Coimbatore, India.
2Research Supervisor, Department of Home Science, Mother Teresa Women’s University, Coimbatore, India.
3Principal and Head, Department of Biochemistry, PSG College of Arts and Science, Coimbatore, India.
*Corresponding Author

Published In:   Volume - 12,      Issue - 2,     Year - 2019


ABSTRACT:
Terminalia bellerica, Withania somnifera, Madhuca longifolia and Sygyzium cumini was selected for the current study based on its potent antimicrobial activity. The poly herbal plant extract was tested against nine clinical bacterial strains that are responsible for the wound infections. The FTIR and GCMS studies of the poly herbal plant extract revealed the presence of functional groups such as phenols, alcohol, amines, carbonyl group and components responsible for antimicrobial properties respectively. The phytochemical analysis showed the presence of bioactive principles such as alkaloids, flavanoids, phenols, steroids and tannins. The poly herbal extract was then coated on the TencelR nonwoven fabric using pad-dry-cure method. The antimicrobial efficacy of the coated fabrics exhibited better inhibitory activity against all the test organisms under the standard AATCC 147. The coated fabric also showed 8 mm zone of inhibition against Candida albicans. The results recommend the use of poly herbal plant extract can potentially be used as a substitute to synthetic agents. Also, it can be employed in non-implantable medical textiles such as wound dressings to prevent the microbial infestation and also to reduce the bio burden in wound therapy.


Cite this article:
Karpagam P, G Manonmani, D Brindha. Phytochemical Screening, Antimicrobial Activity and Antimicrobial Finishing of Polyherbal Extract on Nonwoven Wound Dressing. Research J. Pharm. and Tech 2019; 12(2):632-636. doi: 10.5958/0974-360X.2019.00112.4

Cite(Electronic):
Karpagam P, G Manonmani, D Brindha. Phytochemical Screening, Antimicrobial Activity and Antimicrobial Finishing of Polyherbal Extract on Nonwoven Wound Dressing. Research J. Pharm. and Tech 2019; 12(2):632-636. doi: 10.5958/0974-360X.2019.00112.4   Available on: https://rjptonline.org/AbstractView.aspx?PID=2019-12-2-31


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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