ABSTRACT:
Quercetin has a wide array of pharmacological properties such as antioxidant and anti-inflammatory activities. Scientific study has indicated that quercetin possesses protective effects against toxic agents in several tissues, including brain, lung, heart, liver, kidney, etc. The scientific databases such as MEDLINE, PubMed, Scopus, Web of Science and Google Scholar from 1990 to present was searched to identify online scientific literatures about antidotal and protective effects of quercetin against neurotoxic agents. The keywords for the search were: quercetin, toxic agents, and neurodegenerative disease. This review aims to identify the protective effects of quercetin against neurotoxic agents. This study found that quercetin had protective activities against toxic agents-induced neurotoxicity by modulating oxidative stress, inflammation, and apoptosis pathways. The scientific databases such as MEDLINE, PubMed, Scopus, Web of Science and Google Scholar from 1990 to present was searched to identify online scientific literatures about antidotal and protective effects of quercetin against neurotoxic agents. The keywords for the search were: quercetin, toxic agents, and neurodegenerative disease.