Kishore Manoharan, Navya Ajitkumar Bhaskaran, Lalit Kumar
Kishore Manoharan, Navya Ajitkumar Bhaskaran, Lalit Kumar*
Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576 104, Udupi, Karnataka, India.
Volume - 12,
Issue - 12,
Year - 2019
Background In the present day scenario, where novel drug delivery system and controlled drug delivery systems have been developed over the conventional oral solid dosage forms, pellets emerged as a versatile delivery system. Pelletization is a technique to obtain pellets or spherical particles having a dimensions between 0.5 - 1.5 mm. These multiparticulate systems are either compressed into tablets or filled into capsules. Area covered The following review provides a brief outline on pelletization. In this review, we have discussed on various parameters affecting pelletization, different techniques of pelletization and assessment of pellets. Expert opinion It is expected that the pellatizaiton is an effective and efficient approach which can help in improvement of absorption, bioavailability, stability, etc. Pellets can offer therapeutic advantages with effordable cost. Several studies are performed to address the limitations of numerous drugs.
Cite this article:
Kishore Manoharan, Navya Ajitkumar Bhaskaran, Lalit Kumar. Pellets and Techniques of Pelletization. Research J. Pharm. and Tech. 2019; 12(12): 6157-6164. doi: 10.5958/0974-360X.2019.01070.9