Author(s): Khudhayer J. Kadem, Murad G. Munahi

Email(s): khudheyerbabel@yahoo.com

DOI: 10.5958/0974-360X.2018.00745.X   

Address: Khudhayer J. Kadem, Murad G. Munahi
Department of Chemistry, College of Science, University of Babylon, Iraq
*Corresponding Author

Published In:   Volume - 11,      Issue - 9,     Year - 2018


ABSTRACT:
A series of Schiff’s bases and their novel derivatives (Oxazepines) have been synthesized , 4-hydroxy-3-methoxy benzaldehyde (vanillin) was condensed with different amines to produce the Schiff’s bases in the presence of glacial acetic acid as a catalyst or KOH , novel five 1,3-oxazepine derivatives have been synthesized through reaction of Schiff’s bases with succinic anhydride and maleic anhydride using acidic catalyst. The identification was performed using, FT-IR and1H-NMRspectroscopies. The synthesized1,3-oxazepine derivatives were biologically screened against gram positive (Staphylococcus aureus) and gram negative bacteria (Escherichia coli) . The results was showed excellent to moderate anti-bacterial activity.


Cite this article:
Khudhayer J. Kadem, Murad G. Munahi. Synthesis, Characterization and Biological Evaluation of some Novel 1,3 Oxazepine derivatives from Vanillin Schiff’s Bases. Research J. Pharm. and Tech 2018; 11(9): 4047-4050. doi: 10.5958/0974-360X.2018.00745.X

Cite(Electronic):
Khudhayer J. Kadem, Murad G. Munahi. Synthesis, Characterization and Biological Evaluation of some Novel 1,3 Oxazepine derivatives from Vanillin Schiff’s Bases. Research J. Pharm. and Tech 2018; 11(9): 4047-4050. doi: 10.5958/0974-360X.2018.00745.X   Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-9-60


Recomonded Articles:

Author(s): Amurdhavani. B.S

DOI: 10.5958/0974-360X.2016.00299.7         Access: Closed Access Read More

Author(s): R. Narayana Charyulu, P. Parvathy Devi, Jobin Jose, A. Veena Shetty

DOI: Not Available         Access: Open Access Read More

Author(s): Prasad V. Patrekar, Sachin S. Mali

DOI: Not Available         Access: Open Access Read More

Author(s): A. S. K. Sankar, B. Datchayani, N. Balakumaran, Mohammed Rilwan, R. Subaranjani

DOI: 10.5958/0974-360X.2017.00047.6         Access: Open Access Read More

Author(s): Priya P. Munshi, D.S. Mohale, R. Akkalwar, A.V. Chandewar

DOI: Not Available         Access: Open Access Read More

Author(s): Jino Elsa Thomas, Usha Y Nayak*, Jagadish PC, Koteshwara KB

DOI: 10.5958/0974-360X.2017.00007.5         Access: Open Access Read More

Author(s): Kalpana Kamnoore, M P Venkatesh, Balamuralidhara V, T M Pramod Kumar

DOI: 10.5958/0974-360X.2020.00276.0         Access: Open Access Read More

Author(s): S. Valarmathi, M. Senthil Kumar, Vignesh Sharma, Mohamed Imran, Mohanasundaram

DOI: 10.5958/0974-360X.2020.00043.8         Access: Open Access Read More

Author(s): Peethala Prathyusha, Raja Sundararajan, Palyam Bhanu, Mathrusri Annapurna Mukthinuthalapati

DOI: 10.5958/0974-360X.2020.00507.7         Access: Open Access Read More

Author(s): Vijayalakshmi. S , Disalva. X, Chittaranjan Srivastava, Arun A

DOI: 10.5958/0974-360X.2019.00520.1         Access: Open Access Read More

Author(s): Naveen M.R., Santhosh Y.L., Satish Kumar B.P

DOI: Not Available         Access: Open Access Read More

Author(s): Katare Varsha B., Bhutkar M. A., Kumbhar A. P., Pol S. K., Katare P. B.

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags