Author(s):
Bharadwaj, Gopinath P
Email(s):
Email ID Not Available
DOI:
10.5958/0974-360X.2018.00733.3
Address:
Bharadwaj1, Dr. Gopinath P2
1BDS, Saveetha Dental College, Saveetha University, Chennai
2Senior Lecturer, Department of Microbiology, Saveetha Dental College, Saveetha University, Chennai
*Corresponding Author
Published In:
Volume - 11,
Issue - 9,
Year - 2018
ABSTRACT:
The resistance to antibiotic employed against staphylococcal isolates is an alarming problem. This has led to show intrest in using Macrolid-Lincosamide Streptogramin B (MLSB) antibiotics to treat infection produce by S. aureus. In vitro test for detecting clindamycin suspectibility may fail to detect inducible clindamycin resistance due to presence of erm gene which results in treatment failure. A total of 20 clinical isolates of S.aereus were subjected to antibiotics suspectibility testing by disc diffusion method. Inducible resistance to clindamycin was detected by D-test as per CLSI guideline.20% isolates of were positive for iMLB phenotype, while 15% isolates were belong to MS phenotypes. This study showed that D-test can be used as a routine method in detecting inducible clindamycin resistance along with disc diffusion in S.aureus.
Cite this article:
Bharadwaj, Gopinath P. Detection of Inducible Clindamycin Resistance among Clinical Isolates of Staphylococcus aureus. Research J. Pharm. and Tech 2018; 11(9): 3990-3992. doi: 10.5958/0974-360X.2018.00733.3
Cite(Electronic):
Bharadwaj, Gopinath P. Detection of Inducible Clindamycin Resistance among Clinical Isolates of Staphylococcus aureus. Research J. Pharm. and Tech 2018; 11(9): 3990-3992. doi: 10.5958/0974-360X.2018.00733.3 Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-9-48