Author(s): Sunkara Mrunal Chaithanya, Mukthinuthalapati Mathrusri Annapurna

Email(s): mrunal.chaitanya@gmail.com

DOI: 10.5958/0974-360X.2018.00572.3   

Address: Sunkara Mrunal Chaithanya*, Mukthinuthalapati Mathrusri Annapurna
Department of Pharmaceutical Analysis and Quality Assurance, GITAM Institute of Pharmacy,
GITAM (Deemed to be University), Visakhapatnam-530045, India
*Corresponding Author

Published In:   Volume - 11,      Issue - 7,     Year - 2018


ABSTRACT:
A new RP-HPLC method has been developed and validated for the simultaneous determination of Ketorolac tromethamine and Fluorometholone pharmaceutical formulations. Shimadzu Model CBM-20A/20 Alite with C8 Phenomenex column (250 mm × 4.6 mm i.d., 5 µm particle size) was used for the proposed work with a mixture of 0.1M ammonium formate and methanol as mobile phase and flow rate 0.8 ml/min (UV detection at 241 nm). The linear regression equation was found to be y = 35207x + 29529 R² = 0.9995 for Fluorometholone and y = 68207x + 57590 R² = 0.9997 for Ketorolac tromethamine and the method was validated.


Cite this article:
Sunkara Mrunal Chaithanya, Mukthinuthalapati Mathrusri Annapurna. Method Development and Validation of a new RP-HPLC method for the simultaneous Assay of Ketorolac Tromethamine and Fluorometholone. Research J. Pharm. and Tech 2018; 11(7): 3119-3122. doi: 10.5958/0974-360X.2018.00572.3

Cite(Electronic):
Sunkara Mrunal Chaithanya, Mukthinuthalapati Mathrusri Annapurna. Method Development and Validation of a new RP-HPLC method for the simultaneous Assay of Ketorolac Tromethamine and Fluorometholone. Research J. Pharm. and Tech 2018; 11(7): 3119-3122. doi: 10.5958/0974-360X.2018.00572.3   Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-7-71


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DOI: 10.5958/0974-360X 

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