Author(s): Leonid Kayukov, Lubov Agarkova, Tatiana Agarkova, Vitalyi Shipakov, Irina Zakharova, Irina Bukharina

Email(s): agarkova@mail.ru

DOI: 10.5958/0974-360X.2018.00560.7   

Address: Leonid Kayukov1, Lubov Agarkova1, Tatiana Agarkova1*, Vitalyi Shipakov2, Irina Zakharova3, Irina Bukharina1
1Research Institute of Obstetrics, Gynecology and Perinatology, Tomsk National Research Medical Center, Russian Academy of Sciences.
2Department of Anesthesiology, Reanimatology and Intensive Care, Siberian State Medical University, Tomsk, Russia.
3Obstetrics and Gynecology Department , Siberian State Medical University, Tomsk, Russia.
*Corresponding Author

Published In:   Volume - 11,      Issue - 7,     Year - 2018


ABSTRACT:
The purpose is to develop principles of intra- and postoperative preventive measures against thromboembolic complications in gynaecologic patients with haemostasis system defects. The methods of examining the haemostasis system status included the determination of the platelets level, platelets aggregation, activated partial thromboplastin time (APTT), plasma coagulation time, prothrombin time, international normalized ratio (INR), concentration of fibrinogen in plasma, antithrombin III activity, and D-dimer. A comprehensive analysis of the haemostasis and fibrinolysis system was carried out with the ARP-01 “Mednord” portable analyser of blood rheological properties. Obtained results were statistically processed with the SPSS v.20.0 software (Providence Software Solutions, Inc., USA) with Student’s t-test and Mann-Whitney U-test. The comparison of dependent variables used the Wilcoxson W-test. The significance of differences in qualitative attributes was analysed during the frequency analysis with Fisher’s exact test and the chi-squared test. The study suggests two differentiated approaches to the prescription of intravenous laser irradiation of blood, based on hemocoagulogram indicators that reflect the structural and chronometric properties of the formed clot.


Cite this article:
Leonid Kayukov, Lubov Agarkova, Tatiana Agarkova, Vitalyi Shipakov, Irina Zakharova, Irina Bukharina. Disorders of the Functional State of the Haemostatic System during Intraoperative and Postoperative Anesthesia and their Prevention. Research J. Pharm. and Tech 2018; 11(7): 3043-3048. doi: 10.5958/0974-360X.2018.00560.7

Cite(Electronic):
Leonid Kayukov, Lubov Agarkova, Tatiana Agarkova, Vitalyi Shipakov, Irina Zakharova, Irina Bukharina. Disorders of the Functional State of the Haemostatic System during Intraoperative and Postoperative Anesthesia and their Prevention. Research J. Pharm. and Tech 2018; 11(7): 3043-3048. doi: 10.5958/0974-360X.2018.00560.7   Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-7-59


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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