Author(s): Mukthinuthalapati Mathrusri Annapurna, Debi Prasad Pradhan, Krishna Chaitanya Routhu

Email(s): mannapurna.mukthinuthalapati@gitam.edu

DOI: 10.5958/0974-360X.2018.00554.1   

Address: Mukthinuthalapati Mathrusri Annapurna*, Debi Prasad Pradhan, Krishna Chaitanya Routhu
Department of Pharmaceutical Analysis and Quality Assurance, GITAM Institute of Pharmacy,
GITAM (Deemed to be University), Visakhapatnam, Andhra pradesh-530045, India.
*Corresponding Author

Published In:   Volume - 11,      Issue - 7,     Year - 2018


ABSTRACT:
Abiraterone is used for the treatment of prostate cancer for men. Abiraterone is available as Abiraterone acetate. Food and drug administration approves Abiraterone for treatment of men with advanced prostate cancer. A new stability indicating RP-HPLC method has been proposed for the quantification of Abiraterone. Capcell PAK C18 column (100 mm × 4.6 mm i.d., 3 µm particle size) was used for the chromatographic study of Abiraterone acetate with mobile phase mixture 0.1 % acetic acid and acetonitrile (11:89 v/v) (Flow rate: 1.2 mL/min) on Shimadzu Model CBM-20A/20 Alite HPLC system (PDA detector). Forced degradation studies were performed and the method was validated.


Cite this article:
Mukthinuthalapati Mathrusri Annapurna, Debi Prasad Pradhan, Krishna Chaitanya Routhu. Stability Indicating RP-HPLC method for the determination of Abiraterone (An Anti-Cancer Drug). Research J. Pharm. and Tech 2018; 11(7): 3007-3012. doi: 10.5958/0974-360X.2018.00554.1

Cite(Electronic):
Mukthinuthalapati Mathrusri Annapurna, Debi Prasad Pradhan, Krishna Chaitanya Routhu. Stability Indicating RP-HPLC method for the determination of Abiraterone (An Anti-Cancer Drug). Research J. Pharm. and Tech 2018; 11(7): 3007-3012. doi: 10.5958/0974-360X.2018.00554.1   Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-7-53


Recomonded Articles:

Author(s): Nimbalkar V.V., Pansare P.M., Nishane B.B.

DOI: 10.5958/0974-360X.2015.00310.8         Access: Open Access Read More

Author(s): A. S. K. Sankar, B. Datchayani, N. Balakumaran, Mohammed Rilwan, R. Subaranjani

DOI: 10.5958/0974-360X.2017.00047.6         Access: Open Access Read More

Author(s): Trophimus Gnanabagyan Jayakaran, Vignesh R, Shankar P

DOI: 10.5958/0974-360X.2019.00700.5         Access: Open Access Read More

Author(s): Muhammad Hamdan, Noorhamdani AS, Masruroh Rahayu, Mohammmad Hasan Machfoed

DOI: 10.5958/0974-360X.2019.01020.5         Access: Open Access Read More

Author(s): Peethala Prathyusha, Raja Sundararajan, Palyam Bhanu, Mathrusri Annapurna Mukthinuthalapati

DOI: 10.5958/0974-360X.2020.00507.7         Access: Open Access Read More

Author(s): V. Shirisha, Somsubhra Ghosh, B. Rajni, David Banji

DOI: Not Available         Access: Open Access Read More

Author(s): Rekha Rajendran, R Hemachander, T Ezhilarasan, C Keerthana, DL Saroja, KV Saichand, Mohamed Gasim Abdullah

DOI: Not Available         Access: Open Access Read More

Author(s): Narendra Chotai, Vishnu Patel, Harsha Patel, Uren Patel, Rajendra Kotadiya

DOI:         Access: Open Access Read More

Author(s): Vijayalakshmi. S , Disalva. X, Chittaranjan Srivastava, Arun A

DOI: 10.5958/0974-360X.2019.00520.1         Access: Open Access Read More

Author(s): Khan MU, Ghafoor A, Ishaq MT, Hasan B, Salman A, Tengku MA, Zubaidi AL, Nodrin S, Atif AB, Ilyas MN

DOI: 10.5958/0974-360X.2018.00794.1         Access: Open Access Read More

Author(s): Vaseeha Banu T.S., Sandhya K.V., K.N. Jayaveera

DOI: Not Available         Access: Open Access Read More

Author(s): M. Sumithra, Avantika Prabhabanik

DOI: 10.5958/0974-360X.2017.00036.1         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags