Author(s): Jeong-Suk Kim, Jeong-Sook Park

Email(s): pk0207@nambu.ac.kr

DOI: 10.5958/0974-360X.2018.00553.X   

Address: Jeong-Suk Kim1, Jeong-Sook Park*2
1Department of Nursing, Nambu University, 23 Jungang-ro, Gwangsan-gu, Gwangju, 62271, Korea
2Department of Nursing, Nambu University, 23 Jungang-ro, Gwangsan-gu, Gwangju, 62271, Korea,
*Corresponding Author

Published In:   Volume - 11,      Issue - 7,     Year - 2018


ABSTRACT:
Background/Objectives: This study aims to demonstrate pro-inflammatory cytokine production inhibitory effects using everlasting oil. Methods/Statistical analysis:Thus, This paper was carried out to see secretion of NO, inflammatory cytokine ,TNF-a , IL-1ß using the macrophages of LPS-treated mice. The cytotoxicity test was used 96 AQueous One solution cell proliferation assay. No Detection kit was used to measure No ,the production of pro-inflammatory cytokine was measured using ELISA kit. Findings: As a result, everlasting oil had no cytotoxicity at 5 ug/mL to 500 ug/mL and significantly inhibited the production of NO as well as TNF-a, IL-1ß. In the RAW 264.7 mousemacrpphage cells,Pro-inflammatory cytokine production inhibitory effects are likely to be diversely utilized as basic physiological activity data and functional materials to demonstrate anti-inflammatory properties of everlasting oil. Improvements/Applications: In conclusion, this study can be used to a basic data to objectively demonstrate the physiological activity of immunological mechanism associated with the anti-inflammatory action of everlasting oil, but it is necessary to conduct studies on anti-inflammation.


Cite this article:
Jeong-Suk Kim, Jeong-Sook Park. Pro-inflammatory Cytokine Production Inhibitory Effects of Everlasting Oil. Research J. Pharm. and Tech 2018; 11(7): 3003-3006. doi: 10.5958/0974-360X.2018.00553.X

Cite(Electronic):
Jeong-Suk Kim, Jeong-Sook Park. Pro-inflammatory Cytokine Production Inhibitory Effects of Everlasting Oil. Research J. Pharm. and Tech 2018; 11(7): 3003-3006. doi: 10.5958/0974-360X.2018.00553.X   Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-7-52


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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