Author(s):
V. Chitra, J. Narayanan
Email(s):
akashnara07@gmail.com , velchitram74@gmail.com
DOI:
10.5958/0974-360X.2018.00538.3 
Address:
Dr. V. Chitra1, J. Narayanan2
1Research Scholar, SRM College of Pharmacy, Department of Pharmacology, SRM University, Kattankulathur Tamil Nadu, India
2Vice Principal and Head, SRM College of Pharmacy, Department of Pharmacology, SRM University, Kattankulathur, TamilNadu, India
*Corresponding Author
Published In:
Volume - 11,
Issue - 7,
Year - 2018
ABSTRACT:
Garciniahanburyi belongs to the family Clusiaceae. The whole plant was dried, extracted to obtain Xanthone rich extract. Phytochemical studies of extract showed the presence of Phenols, Alkaloids, steroids, resins and saponins. Alzheimer’s disease the most common form of dementia, a brain disorder which has been affecting the elderly. The natural sources such as a plants are an abundant source having various medicinal properties. In the present study, Garciniahanburyi has been selected to test for the AChE, BuChE activity by Ellman's method. The anti-oxidant activity has been performed by DPPH assay. The results showed that the extract from Garciniahanburyi could inhibit the activity of AchE and BuChE. It showed a significant % inhibition of AChE at 73.5% and BuChE inhibition of 57.5%. The IC50 values for DDPH scavenging activity was significant when compared with the standard Ascorbic acid.
Cite this article:
V. Chitra, J. Narayanan. In vitro Screening for Anti-Cholinesterase and Anti Oxidant Activity of Extract of Garcinia hanburyi. Research J. Pharm. and Tech 2018; 11(7): 2918-2921. doi: 10.5958/0974-360X.2018.00538.3
Cite(Electronic):
V. Chitra, J. Narayanan. In vitro Screening for Anti-Cholinesterase and Anti Oxidant Activity of Extract of Garcinia hanburyi. Research J. Pharm. and Tech 2018; 11(7): 2918-2921. doi: 10.5958/0974-360X.2018.00538.3 Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-7-37