Author(s): Palak Agrawal, Ajazuddin, Tripti Banjare, Swapnil Gupta, Akansha Bhandarkar, Hemlata Sahu, Shradha Devi Diwedi, Pankaj Sahu, Siddharth Kumar Sahu, Pooja Yadav, Aditi Bhatt, Kailash Sahu, Deeksha Dewangan, Hemlata Thapa, Deepika, Gyanesh Sahu, Mukesh Sharma, D. K. Tripathi, Amit Alexander

Email(s): itsmeamitalex@gmail.com , dramitalexander@gmail.com

DOI: 10.5958/0974-360X.2018.00517.6   

Address: Palak Agrawal, Ajazuddin, Tripti Banjare, Swapnil Gupta, Akansha Bhandarkar, Hemlata Sahu, Shradha Devi Diwedi, Pankaj Sahu, Siddharth Kumar Sahu, Pooja Yadav, Aditi Bhatt, Kailash Sahu, Deeksha Dewangan, Hemlata Thapa, Deepika, Gyanesh Sahu, Mukesh Sharma, D. K. Tripathi, Amit Alexander*
Rungta College of Pharmaceutical Sciences and Research, Kohka-kurud Road, Bhilai, Chhattisgarh, 4900024
*Corresponding Author

Published In:   Volume - 11,      Issue - 7,     Year - 2018


ABSTRACT:
The candesartan cilexetil floating matrix drug delivery system was design to prolong the gastric residence time and improve its bioavailability. The candesartan cilexetil floating matrix tablet was prepared by using direct compression technique. Various natural polymer such as xanthan gum, guar gum as well as synthetic polymer such as hydroxypropyl methyl cellulose used in combination along with other standard excipients. Here, sodium bicarbonate acts as gas-generating agent. The granules undergoes through pre and post compression studies. The tablet evaluated by using various evaluating parameter viz, hardness, friability, weight variation, content uniformity, floating capacity and in vitro drug release studies.


Cite this article:
Palak Agrawal, Ajazuddin, Tripti Banjare, Swapnil Gupta, Akansha Bhandarkar, Hemlata Sahu, Shradha Devi Diwedi, Pankaj Sahu, Siddharth Kumar Sahu, Pooja Yadav, Aditi Bhatt, Kailash Sahu, Deeksha Dewangan, Hemlata Thapa, Deepika, Gyanesh Sahu, Mukesh Sharma, D. K. Tripathi, Amit Alexander. Formulation and Evaluation of directly compressed Floating Tablets of Candesartan Cilexetil for Gastro Retentive Drug Delivery. Research J. Pharm. and Tech 2018; 11(7): 2804-2808. doi: 10.5958/0974-360X.2018.00517.6

Cite(Electronic):
Palak Agrawal, Ajazuddin, Tripti Banjare, Swapnil Gupta, Akansha Bhandarkar, Hemlata Sahu, Shradha Devi Diwedi, Pankaj Sahu, Siddharth Kumar Sahu, Pooja Yadav, Aditi Bhatt, Kailash Sahu, Deeksha Dewangan, Hemlata Thapa, Deepika, Gyanesh Sahu, Mukesh Sharma, D. K. Tripathi, Amit Alexander. Formulation and Evaluation of directly compressed Floating Tablets of Candesartan Cilexetil for Gastro Retentive Drug Delivery. Research J. Pharm. and Tech 2018; 11(7): 2804-2808. doi: 10.5958/0974-360X.2018.00517.6   Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-7-16


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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