Author(s): Pankaj Sahu, Amit Alexander, Palak Agrawal, Tripti Banjare, Akansha Bhandarkar, Swapnil Gupta, Hemlata Sahu, Shradha Devi Diwedi, Siddharth Kumar Sahu, Pooja Yadav, Kailash Sahu, Aditi Bhatt, Deeksha Dewangan, Hemlata Thapa, Deepika, Gyanesh Sahu, Mukesh Sharma, D. K. Tripathi, Ajazuddin

Email(s): write2ajaz@gmail.com , ajazuddin@rungta.ac.in

DOI: 10.5958/0974-360X.2018.00448.1   

Address: Pankaj Sahu, Amit Alexander, Palak Agrawal, Tripti Banjare, Akansha Bhandarkar, Swapnil Gupta, Hemlata Sahu, Shradha Devi Diwedi, Siddharth Kumar Sahu, Pooja Yadav, Kailash Sahu, Aditi Bhatt, Deeksha Dewangan, Hemlata Thapa, Deepika, Gyanesh Sahu, Mukesh Sharma, D. K. Tripathi, Ajazuddin*
Rungta College of Pharmaceutical Sciences and Research, Kohka-kurud road, Bhilai, Chhattisgarh, 4900024
*Corresponding Author

Published In:   Volume - 11,      Issue - 6,     Year - 2018


ABSTRACT:
Orodispersible tablets are those that dissolve or disintegrate quickly in the oral cavity, resulting in solution or suspension. Allergic rhinitis is a high-prevalence chronic respiratory disease with a negative impact on the subject's quality of life, work activities, productivity or school performance as well as on healthcare costs. Because of its benign nature, the importance of this condition is often underestimated. In the present study orodispersible tablet of antihistaminic agent was prepared by direct compression method using crosspovidone, Crosscarmellose as superdisintegrants. The tablets prepared were evaluated for various parameters like various density parameters, thickness, hardness, friability, disintegration time, wetting time and In-vitro dissolution time. All the parameters were found to be within limits. The developed formulation oflevocetirizine batch F6 (crosspovidone) showed good palatability and dispersed within 30 seconds as compare to crosscarmellose sodium.


Cite this article:
Pankaj Sahu, Amit Alexander, Palak Agrawal, Tripti Banjare, Akansha Bhandarkar, Swapnil Gupta, Hemlata Sahu, Shradha Devi Diwedi, Siddharth Kumar Sahu, Pooja Yadav, Kailash Sahu, Aditi Bhatt, Deeksha Dewangan, Hemlata Thapa, Deepika, Gyanesh Sahu, Mukesh Sharma, D. K. Tripathi, Ajazuddin. Formulation and Evaluation of Levocetrizine Orodispersible tablet. Research J. Pharm. and Tech 2018; 11(6): 2429-2433. doi: 10.5958/0974-360X.2018.00448.1

Cite(Electronic):
Pankaj Sahu, Amit Alexander, Palak Agrawal, Tripti Banjare, Akansha Bhandarkar, Swapnil Gupta, Hemlata Sahu, Shradha Devi Diwedi, Siddharth Kumar Sahu, Pooja Yadav, Kailash Sahu, Aditi Bhatt, Deeksha Dewangan, Hemlata Thapa, Deepika, Gyanesh Sahu, Mukesh Sharma, D. K. Tripathi, Ajazuddin. Formulation and Evaluation of Levocetrizine Orodispersible tablet. Research J. Pharm. and Tech 2018; 11(6): 2429-2433. doi: 10.5958/0974-360X.2018.00448.1   Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-6-49


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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