Author(s): Deepika, Amit Alexander, Palak Agrawal, Tripti Banjare, Aditi Bhatt, Swapnil Gupta, Akansha Bhandarkar, Hemlata Sahu, Shradha Devi Diwedi, Siddharth Kumar Sahu, Pooja Yadav, Kailash Sahu, Deeksha Dewangan, Hemlata Thapa, Pankaj Sahu, Sonam Soni, Ajay Singh, Mukesh Sharma, D. K. Tripathi, Ajazuddin

Email(s): write2ajaz@gmail.com , ajazuddin@rungta.ac.in

DOI: 10.5958/0974-360X.2018.00426.2   

Address: Deepika1, Amit Alexander1, Palak Agrawal1, Tripti Banjare1, Aditi Bhatt1, Swapnil Gupta1, Akansha Bhandarkar1, Hemlata Sahu1, Shradha Devi Diwedi1, Siddharth Kumar Sahu1, Pooja Yadav1, Kailash Sahu1, Deeksha Dewangan1, Hemlata Thapa1, Pankaj Sahu1, Sonam Soni1, Ajay Singh2, Mukesh Sharma1, D. K. Tripathi1, Ajazuddin1*
1Rungta College of Pharmaceutical Sciences and Research, Kohka-kurud Road, Bhilai, Chhattisgarh, 4900024
2GD Rungta College of Science and Technology, Kohka-kurud Road, Bhilai, Chhattisgarh, 4900024
*Corresponding Author

Published In:   Volume - 11,      Issue - 6,     Year - 2018


ABSTRACT:
The main objective of the present investigation was to formulate Risperidone immediate release tablet. Risperidone, an antipsychotic drug mainly act as a D2 and 5HT2A receptor antagonist. Superdisintegrants agents like kollidon and citric acid were used and compressed into tablet by direct compression method. Risperidone is mainly used to treat schizophrenia bipolar disorder. The six formulations having different concentration of superdisintegrants were prepared and formulation blend was examined for angle of repose, bulk density tapped density and compressibility. The tablet were evaluated for various parameters like hardness, thickness, friability, weight variation, disintegration time and invitro dissolution time, all the parameter were found within limits.


Cite this article:
Deepika, Amit Alexander, Palak Agrawal, Tripti Banjare, Aditi Bhatt, Swapnil Gupta, Akansha Bhandarkar, Hemlata Sahu, Shradha Devi Diwedi, Siddharth Kumar Sahu, Pooja Yadav, Kailash Sahu, Deeksha Dewangan, Hemlata Thapa, Pankaj Sahu, Sonam Soni, Ajay Singh, Mukesh Sharma, D. K. Tripathi, Ajazuddin. Formulation and Evaluation of immediate release tablet of Risperidone. Research J. Pharm. and Tech 2018; 11(6): 2301-2305. doi: 10.5958/0974-360X.2018.00426.2

Cite(Electronic):
Deepika, Amit Alexander, Palak Agrawal, Tripti Banjare, Aditi Bhatt, Swapnil Gupta, Akansha Bhandarkar, Hemlata Sahu, Shradha Devi Diwedi, Siddharth Kumar Sahu, Pooja Yadav, Kailash Sahu, Deeksha Dewangan, Hemlata Thapa, Pankaj Sahu, Sonam Soni, Ajay Singh, Mukesh Sharma, D. K. Tripathi, Ajazuddin. Formulation and Evaluation of immediate release tablet of Risperidone. Research J. Pharm. and Tech 2018; 11(6): 2301-2305. doi: 10.5958/0974-360X.2018.00426.2   Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-6-27


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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