Author(s):
Rahamat Unissa, Devaragattu Bhargav Varma, Naga Santhosh Kesana, Chekalta Srinivas, Baddanapally Shalem Raj
Email(s):
srunissa@gmail.com , brudevaragattu@gmail.com , santhoshgtr35@gmail.com , chsrinivas998@gmail.com , shalemrajbaddanapally@gmail.com.
DOI:
10.5958/0974-360X.2018.00409.2 
Address:
Rahamat Unissa*, Devaragattu Bhargav Varma, Naga Santhosh Kesana, Chekalta Srinivas, Baddanapally Shalem Raj
Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Malla Reddy College of Pharmacy, Maisammaguda, Dhulapally, Secunderabad, Telangana, India
*Corresponding Author
Published In:
Volume - 11,
Issue - 6,
Year - 2018
ABSTRACT:
Hepatocellular carcinoma (HCC) is one of the most common types of malignancies that carries poor prognosis worldwide. Accumulating evidences suggest the beneficial effects of amino acid-depleting enzymes in lowering the risk of various cancers. Herein, we investigated the in vitro antioxidant (DPPH ) and anticancer effects of L-glutaminase produced by Idiomarina sediminum; H1695 against Hep-G2 cell lines by MTT assay. Collectively, these findings indicate a crucial role of L-glutaminase in liver cancer.
Cite this article:
Rahamat Unissa, Devaragattu Bhargav Varma, Naga Santhosh Kesana, Chekalta Srinivas, Baddanapally Shalem Raj. In Vitro cytotoxicity of L-Glutaminase against Hep-G2 cell lines. Research J. Pharm. and Tech 2018; 11(6): 2213-2216. doi: 10.5958/0974-360X.2018.00409.2
Cite(Electronic):
Rahamat Unissa, Devaragattu Bhargav Varma, Naga Santhosh Kesana, Chekalta Srinivas, Baddanapally Shalem Raj. In Vitro cytotoxicity of L-Glutaminase against Hep-G2 cell lines. Research J. Pharm. and Tech 2018; 11(6): 2213-2216. doi: 10.5958/0974-360X.2018.00409.2 Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-6-10