Author(s): S. Sarumathy, T. S. Shanmugarajan, K. G. Suresh Rao, N. Benazeer Begum

Email(s): mailshanmugarajan@gmail.com , saruprabakar@gmail.com

DOI: 10.5958/0974-360X.2018.00291.3   

Address: S. Sarumathy1, T. S. Shanmugarajan*2, K. G. Suresh Rao3, N. Benazeer Begum4
1Ph. D. Research Scholar, Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai-600117, India.
2*Professor, Department of Pharmaceutics, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai-600117, India.
3Department of Cardiac Anaesthesiologist and Cardiac Critical Care, Fortis Malar Hospital, Chennai, India.
4Pharm. D, Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai-600117, India
*Corresponding Author

Published In:   Volume - 11,      Issue - 4,     Year - 2018


ABSTRACT:
Purpose: The aim of the study is to determine the significance of assessment of various clinical laboratory parameters as the early indicators of myocardial infarction (MI) in diabetic, hypertensive and hyperlipidemic patients with asymptomatic coronary artery disease (CAD). Materials/Methods: This retrospective study was carried out in a tertiary care hospital during the period of June 2015 to Sep 2015. Medical records of 110 MI patients who had diabetes mellitus, hypertension and hyperlipidemia admitted during the period of 2012 to 2014 were collected and analysed. The laboratory parameters such as blood pressure (BP), glycated haemoglobin (HbA1c), blood sugar and lipid profile values were collected from the case sheets of the MI patients 3 months before the occurrence of MI. Results: The average age group of the study population was found to be 63.16±13.89 years. 80.91% Of the patients were male and 19.09% were female. Most of the patients were overweight (39.09%) and had significant social habits such as smoking (51.82%), alcoholic (37.27%) and tobacco use (16.36%). Elevated levels of BP, total cholesterol, triglycerides (TGLs), low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), fasting blood glucose (FBG), random blood glucose (RBG), post prandial blood glucose (PPBG) and HbA1c were seen in the study group. Conclusion: Thus BP, HbA1c, blood sugar and lipid profiles were elevated in these high risk patients 3 months before the occurrence of MI. Henceforth these clinical parameters can be used as a prognostic marker in assessing the cardiac risk of developing MI in diabetic, hypertensive and hyperlipidemic patients with asymptomatic CAD.


Cite this article:
S. Sarumathy, T. S. Shanmugarajan, K. G. Suresh Rao, N. Benazeer Begum. Significance of Clinical Laboratory Values as early indicators of Myocardial Infarction - A Retrospective Study. Research J. Pharm. and Tech 2018; 11(4): 1563-1565. doi: 10.5958/0974-360X.2018.00291.3

Cite(Electronic):
S. Sarumathy, T. S. Shanmugarajan, K. G. Suresh Rao, N. Benazeer Begum. Significance of Clinical Laboratory Values as early indicators of Myocardial Infarction - A Retrospective Study. Research J. Pharm. and Tech 2018; 11(4): 1563-1565. doi: 10.5958/0974-360X.2018.00291.3   Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-4-55


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