Author(s): Santhosh Kumar R, Asha Devi. S

Email(s): ashaselvaraj74@gmail.com

DOI: 10.5958/0974-360X.2018.00228.7   

Address: Santhosh Kumar R, Asha Devi. S*
Department of Biomedical Sciences, School of Biosciences and Technology, VIT, Tamil Nadu Vellore-14
*Corresponding Author

Published In:   Volume - 11,      Issue - 3,     Year - 2018


ABSTRACT:
Heavy metals toxicity is a major threat to public health throughout the world. Considerably, Lead exposure is decidedly common and capable of inducing permanent damage to various organs. Several evidence were showing the risk of lead toxicity on male reproductive system. But there is no comprehensive data available to deliver the adverse effects of lead in male reproductive parameters. So, this review attempts to explore the negative effects caused by lead exprosure’s in experimental and clinical studies. Several studies shown that there is significant alteration takes place in antioxidant level, semen parametres, spermatogenesis and steroidogenesis. In addition, it also upadtes the reader about the possible adverse effects arise in gene expression and alteration takes place in reproductive hormones.


Cite this article:
Santhosh Kumar R, Asha Devi. S. Lead Toxicity on Male Reproductive System and its Mechanism: A Review. Research J. Pharm. and Tech. 2018; 11(3): 1228-1232. doi: 10.5958/0974-360X.2018.00228.7


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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