ABSTRACT:
The study included two aspects: study the effect of sodium fluoride on the level of liver enzymes, the oxidation system of Glutathione (GSH), on the Malondialdehyde (MDA), concentrations of urea and creatinine. In addition to its effect on the tissues of liver and kidneys in male white rats. And the study of the protective effect of antioxidants, selenium, vitamin C in garlic on sodium fluoride toxicity, 30 adult male rats were used and randomly divided into three equal groups. The control group was given water only, and the treatment group T1 was given sodium fluoride at a concentration of (20 mg / Kg) of body weight and treatment group (T2) were injected with sodium fluoride (20 mg / kg) and water garlic extract with a concentration of (125 mg / kg) body weight. The results showed that the effect of sodium fluoride was significant. And that the antioxidants, selenium and vitamin C contained in garlic gave a significant effect in inhibiting the toxicity of sodium fluoride used.