Author(s):
Sridharan Balasundaram, Parameswari Ranganathan, Kamini A Rao
Email(s):
tbsridharan@vit.ac.in
DOI:
10.5958/0974-360X.2018.00125.7 
Address:
Sridharan Balasundaram1*, Parameswari Ranganathan2, Kamini A Rao3
1Plant Biotechnology Lab (National Tea Research Foundation Scheme), VIT University, Vellore, Tamil Nadu, India
2Gene Cloning and Technology Lab, Department of Bio Medical Sciences and Technology, VIT University, Vellore, Tamil Nadu, India
3Andrology Unit, ART Medicine, Milann Hospital, Bangalore, Karnataka, India.
*Corresponding Author
Published In:
Volume - 11,
Issue - 2,
Year - 2018
ABSTRACT:
Objective: To evaluate the TPP- ZnO nano particle cyto toxic activity against smoking influenced spermatozoa
Design: An experimental study
Setting: Gene Cloning and Technology Lab, VIT University, Vellore,
Patient(s): chronic smokers who came for first time for infertility issues
Intervention(s): Tea poly phenol (TPP) mixed zinc oxide nanoparticle with smoker’s semen against untreated control was analyzed.
Main Outcome Measure (s): Spermatozoa motility, viability and appearance of morphology.
Result(s): TPP mixed ZnO nano particle will give maximum (5%) of motility and MTT- IC50 shows the maximum viability (P<0.001) with positive morphological changes which near to untreated control.
Conclusion(s): Metal toxicity from smoking effect on sperm motility and viability was reduced or improved with another natural antioxidant of TPP through ZnO nano delivery.
Cite this article:
Sridharan Balasundaram, Parameswari Ranganathan, Kamini A Rao. Tea Poly Phenol - Zinc Oxide nano Particle effects on Infertile Smoker’s Spermatozoa- A Short Report. Research J. Pharm. and Tech 2018; 11(2):667-670. doi: 10.5958/0974-360X.2018.00125.7
Cite(Electronic):
Sridharan Balasundaram, Parameswari Ranganathan, Kamini A Rao. Tea Poly Phenol - Zinc Oxide nano Particle effects on Infertile Smoker’s Spermatozoa- A Short Report. Research J. Pharm. and Tech 2018; 11(2):667-670. doi: 10.5958/0974-360X.2018.00125.7 Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-2-47