Research Journal of Pharmacy and Technology

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0974-360X (Online)
0974-3618 (Print)


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A Prospective Study on Combinational Drug Efficacy in Hypertensive Patients

Author(s): S. Yeswanthi, S. Jayakumari

Email(s): syeswanthi1994@gmail.com

DOI: 10.5958/0974-360X.2018.00093.8   

Address: S. Yeswanthi *, S. Jayakumari
Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels University Chennai.
*Corresponding Author

Published In:   Volume - 11,      Issue - 2,     Year - 2018

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ABSTRACT:
AIM AND OBJECTIVES : The main of aim of this study is to evaluate the combination drug efficacy in hypertensive patients and also reduction of blood pressure by using combination drugs. METHODS AND MATERIALS: This study which includes prospective monitoring of hypertensive patients who are taking different type of combination durgs to reduce blood pressure. This is prospective study done in hypertensive patients. The statistical method used in the study is student t test. RESULTS : Totally 100 patients were included in the study. Three month was readings were taken. 1st month reading is taken as initial value and 3rd month reading is taken as final value. The baseline blood pressure was reduced from 171.2±3.2 to 137.1±2.6 in systolic blood pressure where as diastolic blood is reduced from 101.20±3.2 to 87.10±2.6 of patients using group D. The other group combinations also have slight changes in the reduction of blood pressure. The combination therapy shows greater efficacy in hypertensive patients. CONCLUSION: The percentage reduction of blood pressure after using group D was more than compared with other combinations. This study concludes that combination drugs shows efficacy in hypertensive patients.


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Cite this article:
S. Yeswanthi, S. Jayakumari. A Prospective Study on Combinational Drug Efficacy in Hypertensive Patients. Research J. Pharm. and Tech 2018; 11(2):509-512. doi: 10.5958/0974-360X.2018.00093.8


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DOI: 10.5958/0974-360X 

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Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.    
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