Author(s):
K. Sonia, M. Nappinnai, P. Panneerselvam
Email(s):
soniapharm68@yahoo.com
DOI:
10.5958/0974-360X.2018.00877.6 
Address:
K. Sonia*1, Dr. M. Nappinnai2, Dr. P. Panneerselvam3
1Part Time Ph.D Scholar, The Tamilnadu Dr. M.G.R Medical University, Chennai, Tamil Nadu
2Professor, Surya School of Pharmacy, Vikiravandi–605 652 Villupuram Dt. Tamil Nadu
3Professor, CL Baid Mehta College of Pharmacy, Chennai, Tamil Nadu
*Corresponding Author
Published In:
Volume - 11,
Issue - 11,
Year - 2018
ABSTRACT:
A simple, specific, accurate and stability-indicating Ultra Violet chromatographic method was developed for the simultaneous determination of Telmisartan and Amlodipine besylate by simultaneous equation method. The absorbance of wavelength for two drugs was found to be 240nm and 230nm. Linearity was established for Telmisartan and Amlodipine besylate in the range of 0-6µg/ml and 0-25µg/ml, respectively. The percentage recoveries of Telmisartan and Amlodipine besylate were found to be in the range of 100.57% and 100.35%, respectively. Both the drugs were subjected to acid, alkali and neutral hydrolysis, oxidation, dry heat, photolytic and UV degradation. This method can be successfully employed for simultaneous quantitative analysis of Telmisartan and Amlodipine besylate in bulk drugs and formulations.
Cite this article:
K. Sonia, M. Nappinnai, P. Panneerselvam. Stability Indicating UV Method for Simultaneous Determination of Telmisartan and Amlodipine Besylate. Research J. Pharm. and Tech 2018; 11(11): 4825-4828. doi: 10.5958/0974-360X.2018.00877.6
Cite(Electronic):
K. Sonia, M. Nappinnai, P. Panneerselvam. Stability Indicating UV Method for Simultaneous Determination of Telmisartan and Amlodipine Besylate. Research J. Pharm. and Tech 2018; 11(11): 4825-4828. doi: 10.5958/0974-360X.2018.00877.6 Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-11-9