Author(s):
Ramandeep Singh, Ashutosh Upadhayay, M. K. Kale
Email(s):
ramandeepsinghbedi@yahoo.com
DOI:
10.5958/0974-360X.2018.00925.3 
Address:
Ramandeep Singh1*, Ashutosh Upadhayay1, M. K. Kale2
1Department of Pharmacy, Faculty of Allied Health Sciences, Mahatma Jyoti Rao Phoole University, Achrol, Jaipur, India.
2Konkan Gyanpeeth Rahul Dharkar College of Pharmacy and Research Institute
Ladiwali Village, Karjat, Maharashtra 410201
*Corresponding Author
Published In:
Volume - 11,
Issue - 11,
Year - 2018
ABSTRACT:
Cisplatin is an alkylating agent which is used to treat a number of cancers. It is generally used in the treatment of advanced bladder cancers, liver cancer, metastatic ovarian cancers, and metastatic testicular cancer. It is also used in other cancers like, testicular, ovarian, bladder, head and neck, esophageal, small and non-small cell lung, breast, cervical, stomach and prostate cancers. However, apart from its usage in variety of cancers it has side effects too. The major ones are kidney toxicity and Ototoxicity (hearing loss). However, these side effects can be reduced by using novel carriers like liposomes, which may affect its kinetics and enhance its half-life too.
Cite this article:
Ramandeep Singh, Ashutosh Upadhayay, M. K. Kale. Effect of Liposomes as a carrier on Pharmacokinetics of Cisplatin. Research J. Pharm. and Tech 2018; 11(11): 5073-5077. doi: 10.5958/0974-360X.2018.00925.3
Cite(Electronic):
Ramandeep Singh, Ashutosh Upadhayay, M. K. Kale. Effect of Liposomes as a carrier on Pharmacokinetics of Cisplatin. Research J. Pharm. and Tech 2018; 11(11): 5073-5077. doi: 10.5958/0974-360X.2018.00925.3 Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-11-57