Author(s):
R. Balachandar, N. Karmegam, R. Subbaiya
Email(s):
Email ID Not Available
DOI:
10.5958/0974-360X.2018.00836.3 
Address:
R. Balachandar1*, N. Karmegam2, R. Subbaiya3
1Research Scholar, Faculty of Bioengineering, Sathyabama Institute of Science and Technology, Rajiv Gandhi Salai, Chennai-600 119, Tamil Nadu, India.
2Department of Botany, Government Arts College, Salem-636 007, Tamil Nadu, India.
3Associate Professor, Department of Biotechnology, Vinayaka Mission’s Research Foundation, Aarupadi Veedu Institute of Technology, Paiyanoor, Chennai- 600 128, Tamil Nadu, India.
*Corresponding Author
Published In:
Volume - 11,
Issue - 10,
Year - 2018
ABSTRACT:
This present study was aimed to investigate identification of potent actinomycetes that have the ability to produce bioactive compounds was isolated from the vermicast soil collected from Sirumali Hills South India. The ethyl acetate extraction of isolated Streptomyces showed high biological activity against human pathogens. The crude ethyl acetate extract was subjected to TLC to separate compounds. GC-MS and FTIR analaysis were carried out to reveal the structural elucidation of isolated compounds. The identification of bioactive compounds is based on the peak area and retention time. GC-MS chromatogram of extract showed the presence of six bioactive compounds, including saturated and unsaturated fatty acids. The antagonistic activity of Streptomyces sample might be due to the synergistic effect of the identified compounds.
Cite this article:
R. Balachandar, N. Karmegam, R. Subbaiya. Extraction, separation and characterization of bioactive compounds produced by Streptomyces isolated from vermicast soil. Research J. Pharm. and Tech 2018; 11(10): 4569-4574. doi: 10.5958/0974-360X.2018.00836.3
Cite(Electronic):
R. Balachandar, N. Karmegam, R. Subbaiya. Extraction, separation and characterization of bioactive compounds produced by Streptomyces isolated from vermicast soil. Research J. Pharm. and Tech 2018; 11(10): 4569-4574. doi: 10.5958/0974-360X.2018.00836.3 Available on: https://rjptonline.org/AbstractView.aspx?PID=2018-11-10-66