ABSTRACT:
OBJECTIVES: Our objectives are to study the rational use of Atorvastatin in patients in a tertiary care hospital. METHODOLOGY: It was a prospective and observational study which was undertaken in hospital such as various departments, ESI hospital, Ayanavaram for a period of 6 months. A total of 110 patients were included in the study and were followed for the drug utilization evaluation of the study. This study criterion was carried out in In-patients of age greater than 35 years of either gender who are prescribed with HMG-COA reductase inhibitor Atorvastatin. RESULTS: The Drug was found to be prescribed more in males [56%] compared to females [44%]. In the lipid profile study, all the different parameters like Total cholesterol: HDL ratio, HDL: LDL ratio and Triglycerides: HDL ratio was analyzed. Drug interactions were analyzed and reported. CONCLUSION: We conclude that the drug use was found to be rational. Interventions for improving more accurate use of Atorvastatin should be implemented. Further studies from time to time are essential in drug utilization pattern and standard treatment guidelines to be circulated among practicing physicians.