ABSTRACT:
The present work aimed screen the bioactive potential of Sargassum wightii. The acetone, methanol and aqueous extract prepared from S. wightii screened for antimicrobial activity against UTIs causing bacteria. Qualitative phytochemical analysis was performed to find the presence of tannins, saponins, flavanoids, terpenoids, alkaloids and glycosides. In phytochemical studies, aqueous extract has glycosides, saponins, tannins and carbohydrates. Glycosides, saponins, teroenoids, steroids, and tannins are present in acetone extract. Methanol extract has flavonoids, saponins, terpenoids, steroids, tannins and carbohydrates. Acetone extract shows maximum inhibition zone diameter was obtained in P. aeuroginosa and in Enterococcus sp with diameter 24.3±0.42 mm 21.5±0.52 mm, respectively. Similarly, Methanol extract showed maximum inhibition zone with diameter of 26.5±0.86 mm in E. coli and 25.1±0.33 mm P.mirbilis. The aqueous extract (8-13 mm) showed restrained and minimum activity, respectively. The present studies concluded the bioactive potential of methanolic extract of Sargassum wightii effective against various urinary tract infecting pathogens.