Author(s): Rakesh K Sindhu, Mansi Chitkara, Gagandeep Kaur, Preeti Jaiswal, Ashutosh Kalra, Inderbir Singh, Pornsak Sriamornsak

Email(s): rakeshsindhu16@gmail.com

DOI: 10.5958/0974-360X.2017.00319.5   

Address: Rakesh K Sindhu1*, Mansi Chitkara2, Gagandeep Kaur1, Preeti Jaiswal1, Ashutosh Kalra1, Inderbir Singh1, Pornsak Sriamornsak3
1Department of Pharmacognosy and Natural Products, Chitkara College of Pharmacy, Chitkara University, NH-64, Rajpura, Patiala, Punjab- 140401, India
2Nanomaterials Research Laboratory, Department of Applied Sciences, Chitkara University, Rajpura, Patiala – 140401, Punjab, India
3Department of Pharmaceutical Technology, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand
*Corresponding Author

Published In:   Volume - 10,      Issue - 6,     Year - 2017


ABSTRACT:
Transdermal drug delivery is one of the most potential methods for drug application. Though the skin, in particular the stratum corneum, possesses a dreadful barrier to drug penetration thus limiting topical and transdermal bioavailability. So skin penetration enhancement techniques have been developed to improve bioavailability and to increase the range of drugs, the topical and transdermal delivery is a viable option. The technique is generally non-invasive, well accepted by patients and can be used to provide local delivery over several days. Various chemical enhancers are used to improve bioavailability of the drugs such as sulfoxides, fatty acids, azones and non ionic surfactants. This review article presents the comprehensive different aspects of drug delivery by transdermal route with various chemical penetration enhancers.


Cite this article:
Rakesh K Sindhu, Mansi Chitkara, Gagandeep Kaur, Preeti Jaiswal, Ashutosh Kalra, Inderbir Singh, Pornsak Sriamornsak. Skin Penetration Enhancer’s in Transdermal Drug Delivery Systems. Research J. Pharm. and Tech. 2017; 10(6): 1809-1815. doi: 10.5958/0974-360X.2017.00319.5


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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