Author(s):
Ashish A. Gawai, Kishor Charhate, Faisal Shaikh, Amir Khan, Aniruddha Chaubey, K. R. Biyani
Email(s):
drashishgawai@gmail.com
DOI:
10.5958/0974-360X.2017.00314.6 
Address:
Ashish A. Gawai, Kishor Charhate, Faisal Shaikh, Amir Khan, Aniruddha Chaubey, K. R. Biyani
Anuradha College of Pharmacy, Anuradha Nagar, Chikhli, Dist-Buldana, MS-443201, India.
*Corresponding Author
Published In:
Volume - 10,
Issue - 6,
Year - 2017
ABSTRACT:
A simple rapid, accurate and precised RP-HPLC method was developed for determination of cardiovascular agent Atorvastatin in pharmaceutical dosage form. The method was validated and demonstrated a wide Linerity Accuracy, Precision, system suitability and Robustness. The proposed method has a simple and rapid procedure. In RP-HPLC method, the analyte were resolved using Methanol: Water (90:10 %v/v) mobile phase with0.7 ml/min flow rate on HPLC pump spectra system 600E with Phenomenex C18 150 × 4.6mm 5 µm column using autochro 3000 software detector for the study. The detection was carried out at 243 nm. This method gave the good resolution and suitable retention time.
Cite this article:
Ashish A. Gawai, Kishor Charhate, Faisal Shaikh, Amir Khan, Aniruddha Chaubey, K. R. Biyani. RP-HPLC method development and validation for hyperlipidemic agent Atorvastatin in pharmaceutical dosage form. Research J. Pharm. and Tech. 2017; 10(6): 1780-1787. doi: 10.5958/0974-360X.2017.00314.6
Cite(Electronic):
Ashish A. Gawai, Kishor Charhate, Faisal Shaikh, Amir Khan, Aniruddha Chaubey, K. R. Biyani. RP-HPLC method development and validation for hyperlipidemic agent Atorvastatin in pharmaceutical dosage form. Research J. Pharm. and Tech. 2017; 10(6): 1780-1787. doi: 10.5958/0974-360X.2017.00314.6 Available on: https://rjptonline.org/AbstractView.aspx?PID=2017-10-6-38