Author(s):
B. C. Revanasiddappa, M. Vijay Kumar, Prashanth Nayak, Ajmal Roshan Ali, Jasmine Kalsi
Email(s):
evergreen_revan@rediffmail.com
DOI:
10.5958/0974-360X.2017.00304.3 
Address:
B. C. Revanasiddappa*, M. Vijay Kumar, Prashanth Nayak, Ajmal Roshan Ali, Jasmine Kalsi
Department of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences of Nitte University, Paneer, Deralakatte, Mangalore-575 018 Karnataka, India
*Corresponding Author
Published In:
Volume - 10,
Issue - 6,
Year - 2017
ABSTRACT:
A new series of Oxazolones (2a-j) were prepared by reacting substituted aromatic aldehydes with N-acetylglycine in presence of anhydrous sodium acetate and acetic anhydride as the solvent medium. The respective Oxazolones (2a-j) were then treated with 4-Amino-1,2,4-triazole (1) in glacial acetic acid medium to yield the title compounds Imidazolinones (3a-j). All the newly synthesized compounds were evaluated for their In –Vitro antibacterial and antifungal activities. The new compounds were assigned on the basis of 1H-NMR, IR, Mass spectral data and elemental analysis.
Cite this article:
B. C. Revanasiddappa, M. Vijay Kumar, Prashanth Nayak, Ajmal Roshan Ali, Jasmine Kalsi. Synthesis and Biological Evaluation of Novel Imidazolinone Derivatives. Research J. Pharm. and Tech. 2017; 10(6): 1726-1729. doi: 10.5958/0974-360X.2017.00304.3
Cite(Electronic):
B. C. Revanasiddappa, M. Vijay Kumar, Prashanth Nayak, Ajmal Roshan Ali, Jasmine Kalsi. Synthesis and Biological Evaluation of Novel Imidazolinone Derivatives. Research J. Pharm. and Tech. 2017; 10(6): 1726-1729. doi: 10.5958/0974-360X.2017.00304.3 Available on: https://rjptonline.org/AbstractView.aspx?PID=2017-10-6-17