Author(s): Poonguzhali Sathish Kumar, Subal Chandra Basak, Sitty Manohar Babu

Email(s): poongi2007@gmail.com

DOI: 10.5958/0974-360X.2017.00247.5   

Address: Poonguzhali Sathish Kumar1*, Subal Chandra Basak1, Sitty Manohar Babu2
1Department of Pharmacy, Annamalai University, Chidambaram, 608002, Tamil Nadu, India
2Department of Pharmacology, SIMS College of Pharmacy, Guntur, 522001, Andhra Pradesh, India.
*Corresponding Author

Published In:   Volume - 10,      Issue - 5,     Year - 2017


ABSTRACT:
Aripiprazole is an antipsychotic medication, works by changing the actions of chemicals in the brain. It is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression). In order to formulate a newer aripiprazole immediate release tablet of strength 30mg we evaluated the physical characteristics and the dissolution profile of the lab scale batch. The dissolution profile of the reference product and in house product was compared. The tablets from the lab scale batch were also subjected to accelerated stability studies. The results obtained were satisfactory and within the specified limits. In-vitro release profiles of the in-house product and reference product were similar. The lab scale batch tablets were found to be stable.


Cite this article:
Poonguzhali Sathish Kumar, Subal Chandra Basak, Sitty Manohar Babu. Formulation and Development of Newer Aripiprazole Immediate Release Tablets. Research J. Pharm. and Tech. 2017; 10(5): 1389-1391. doi: 10.5958/0974-360X.2017.00247.5


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DOI: 10.5958/0974-360X 

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