Author(s): Arun Kumar, Vinita Gupta, Sanchita Singh, Y.K. Gupta

Email(s): ykgbkbiet123@gmail.com

DOI: 10.5958/0974-360X.2017.00208.6   

Address: Arun Kumar1, Vinita Gupta2, Sanchita Singh2, Y.K. Gupta3*
1Research Scholar, School of Applied Sciences Singhania University Pacheri Bari, Jhunjhunu (Raj.), India
2Department of Chemistry, Agra College, Agra, U.P, India
3Head Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, India
*Corresponding Author

Published In:   Volume - 10,      Issue - 4,     Year - 2017


ABSTRACT:
The Chalcone is an aromatic compound that forms the central core for various necessities of biological compounds. The Chalcone is synthesized by Claisen – Schmidt condensation of benzaldehyde derivatives with acetophenone derivatives in dilute ethanolic sodium hydroxide solution at room temperature. The structures of synthesized compounds were investigated by IR Spectroscopy, NMR Spectroscopy and Mass Spectrometry. The antimicrobial activity of the synthesized was evaluated by Filter Paper Disc diffusion Method. The compound 1b showed excellent activity against S. aureus at both concentration i.e. 500µg/ml and1000 µg/ml.


Cite this article:
Arun Kumar, Vinita Gupta, Sanchita Singh, Y.K. Gupta. Synthesis and Physico Chemical Studies of Some Chalcone and Their Derivatives as Potential Antimicrobial Agents. Research J. Pharm. and Tech. 2017; 10(4): 1155-1159. doi: 10.5958/0974-360X.2017.00208.6


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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