ABSTRACT:
Indole, a privileged heterocyclic nucleus has diverse biological activities and inspired chemists to utilise this skeleton as bioactive moiety to synthesize new compounds possessing pharmacological and biological properties. The beauty of indole moiety is that it provides a privilege scaffold for the discovery of different kinds of more active, less toxic novel drugs with different modes of action. Now it is found an abiding interest in the use of indole derivatives against cancer cells, microbes and different kinds of disorder in the human body. Extensive researches on manifold implication of indole and its derivatives have been going on since long specifically in the field of agrochemicals and pharmaceuticals. The review is intended to give a general overview of the various research activities in this expanding field. Here we have made of attempt in highlighting the synthetic routes and characteristics of indole and its derivatives along with their recent developments in pharmacological potential values.