ABSTRACT:
Sodium copper chlorophyllin (SCC) belongs to a group of compound, porphyrins containing a chelated metal ion in the center of the molecule. It is a sodium salt containing copper as the central metal atom with loss of phytol chain. The present study was to extract the sodium copper chlorophyllin from Leucas aspera L. and to check its antibacterial activity. The results show that sodium copper chlorophyllin of Leucas aspera L. has significant anti- bacterial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Salmonella typhi and Pseudomonas aeroginosa with Ampicillin (Std) 20 µg /ml as positive control. The active zone of inhibition was around 6-11 mm against the tested human pathogens .The Minimal Inhibitory Concentration (MIC) was determined and found to be around 31.2-125 µg /ml. This result confirms that the medicinal value of Leucas aspera L. of sodium copper chlorophyllin as an anti bacterial sources .