Author(s):
Mukthinuthalapati Mathrusri Annapurna, Malineni Sushmitha, Kunala Anusha
Email(s):
mathrusri2000@yahoo.com
DOI:
10.5958/0974-360X.2017.00138.X 
Address:
Mukthinuthalapati Mathrusri Annapurna*, Malineni Sushmitha , Kunala Anusha
Department of Pharmaceutical Analysis and Quality Assurance, GITAM Institute of Pharmacy,
GITAM University, Visakhapatnam, India
*Corresponding Author
Published In:
Volume - 10,
Issue - 3,
Year - 2017
ABSTRACT:
Epalrestat is an aldose reductase inhibitor. Three simple, precise and accurate Spectrophotometric methods have been developed for the determination of Epalrestat in pharmaceutical formulations. Spectrophotometric analysis was performed and linearity was observed over the concentration range 0.1-25, 0.5-20 and 0.5-20 µg/ml in phosphate buffer (pH 5.0), phosphate buffer (pH 7.0) and borate buffer (pH 9.0) respectively. All the three methods were validated and can be used for the determination of Epalrestat in pharmaceutical formulations (Tablets).
Cite this article:
Mukthinuthalapati Mathrusri Annapurna, Malineni Sushmitha , Kunala Anusha. New Analytical Techniques for the Determination of Epalrestat in Pharmaceutical Dosage forms by Spectrophotometry. Research J. Pharm. and Tech. 2017; 10(3): 739-742. doi: 10.5958/0974-360X.2017.00138.X
Cite(Electronic):
Mukthinuthalapati Mathrusri Annapurna, Malineni Sushmitha , Kunala Anusha. New Analytical Techniques for the Determination of Epalrestat in Pharmaceutical Dosage forms by Spectrophotometry. Research J. Pharm. and Tech. 2017; 10(3): 739-742. doi: 10.5958/0974-360X.2017.00138.X Available on: https://rjptonline.org/AbstractView.aspx?PID=2017-10-3-16