Author(s): I. Arjun Rao, Moumita Sinha, Manju Sahu, Bharati Ahirwar


DOI: 10.5958/0974-360X.2017.00819.8   

Address: I. Arjun Rao1, Moumita Sinha1*, Manju Sahu1 , Bharati Ahirwar2
1Assistant Professor (Ad-hoc), Department of Forensic Science, Guru Ghasidas University, Bilaspur (C.G.)- 495009
2Head, Department of Forensic Science and Associate Professor, SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur (C.G.)- 495009
*Corresponding Author

Published In:   Volume - 10,      Issue - 12,     Year - 2017

Highly polymorphic nature of the mitochondrial DNA (mtDNA) at the level of population having precise variants of mtDNA influences function mitochondria. Promising confirmation that mechanism at mitochondrial are vital to commonly occurred human diseases, it is believable that variants of mtDNA became a factor to the “missing heritability” of various multifaceted traits. mtDNA genes plays a essential task of oxidative phosphorylation, the alike genetic variants likely to modify the chance of developing a number of diverse disorders, but to date this has not been shown and explained in systematic manner. Numerous facts suggest that mitochondria plays key role in ageing-associated neurodegenerative disorders. Furthermore, haplogroups of mitochondria are related to several aspects of medicine, from habitual ageing to diseases, together with neurodegeneration. Mitochondrial genome polymorphisms might cause troubled generation of energy and leads to formation of large amount of reactive oxygen species, having capability of either susceptibility or shielding role in multiple diseases. In the present review, we emphasize the function of the mitochondrial haplogroups in the pathogenetic rise cause of diseases.

Cite this article:
I. Arjun Rao, Moumita Sinha, Manju Sahu , Bharati Ahirwar. Disease Association of Mitochondrial DNA haplogroups. Research J. Pharm. and Tech 2017; 10(12): 4445-4450. doi: 10.5958/0974-360X.2017.00819.8

Recomonded Articles:

Author(s): V. Padmaharish

DOI: 10.5958/0974-360X.2016.00190.6         Access: Closed Access Read More

Author(s): Koushika Das, Pranit Krishna, Avipsha Sarkar, Shanmuga Sundari Ilangovan, Shampa Sen

DOI: 10.5958/0974-360X.2017.00267.0         Access: Open Access Read More

Author(s): U.S Mahadeva Rao, Khamsah Suryati Mohd, Abdurrazaq Muhammad, Bashir Ado Ahmad, Mohaslinda Mohamad, Rosmawati Mat Ali

DOI: Not Available         Access: Open Access Read More

Author(s): Santhosh Kumar V, Praveen D

DOI: 10.5958/0974-360X.2016.00123.2         Access: Open Access Read More

Author(s): M. Sumithra, Avantika Prabhabanik

DOI: 10.5958/0974-360X.2017.00036.1         Access: Open Access Read More

Author(s): Rahar Sandeep, Nagpal Navneet, Swami Gaurav, Arora Manisha, Bansal Suraj, Goyal Sandeep, Singla Shwali, Singh Preeti, Kapoor Reni

DOI: Not Available         Access: Open Access Read More

Author(s): A. Julius, Ramachandran Vedasendiyar, Archana Devakannan, Sujatha Rajaraman, Balamurugan Rangasamy, V. Saravanan

DOI: 10.5958/0974-360X.2017.00062.2         Access: Open Access Read More

Author(s): Praveen D, Ranadheer Chowdary P, Gandikota Thanmayi, Gangabathina Poojitha, Vijey Aanandhi M

DOI: 0.5958/0974-360X.2016.00047.0         Access: Open Access Read More

Author(s): Saranya, Parthasarathy V, Hariprasad B, Shobha Rani H

DOI: 10.5958/0974-360X.2016.00233.X         Access: Open Access Read More

Author(s): Mahadeva Rao US, San San Oo, Nurul Liana Sabrin, Norsyahira Syazwana Mohd Razali, Khairunnisa Khalid, Nurul Farihah Mohamed Nadzari, Thant Zin

DOI: 10.5958/0974-360X.2017.00065.8         Access: Open Access Read More

Author(s): Yarnykh T.G., Azarenko Iu. M., Buryak M.V., Bubilieva L. A.

DOI: 10.5958/0974-360X.2016.00115.3         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

56th percentile
Powered by  Scopus

SCImago Journal & Country Rank

Recent Articles