Author(s): Vijayalakshmi. A, Suganya M, Pankaj Kumar Giri, Jayakumari. S, Shanmugasundaram P.

Email(s): avijibaskaran@gmail.com

DOI: 10.5958/0974-360X.2017.00052.X   

Address: Vijayalakshmi. A*, Suganya M, Pankaj Kumar Giri, Jayakumari. S, Shanmugasundaram P.
Department of Pharmacognosy, School of Pharmaceutical Sciences, VISTAS, Vels University, Pallavaram, Chennai-117, Tamilnadu, India.
*Corresponding Author

Published In:   Volume - 10,      Issue - 1,     Year - 2017


ABSTRACT:
The present study aimed to evaluate anti-asthmatic activity of a classical Siddha formulation Seenthil chooranam (SC) by mast cell stabilizing effect and broncho dilator property by in-vivo method. Preliminary phytochemical and HPTLC analysis of SC were determined as per standard protocols. Phytochemical analysis of aqueous extract gave positive test for carbohydrates, phenols, glycosides, saponins, flavonoids, tannins and terpenoids. HPTLC finger print analysis of the aqueous extract showed the presence of possible number of components. The results of the in-vivo study demonstrate that SC has potent broncho dilator property with significant (***p<0.001) mast cell stabilizing activity and decrease in leukocytosis in dose dependent manner. These findings are clearly indicative of the role of SC as potent inhibitor of mast cell degranulation and ability to control the leukocytosis, have bronchodilation and hence can be used for the management of asthma supporting the traditional claims


Cite this article:
Vijayalakshmi. A, Suganya M, Pankaj Kumar Giri, Jayakumari. S, Shanmugasundaram P.. Bronchodilator and Mast Cell Stabilizer Effect of Siddha Formulation Seenthil Chooranam. Research J. Pharm. and Tech. 2017; 10(1): 252-256. doi: 10.5958/0974-360X.2017.00052.X


Recomonded Articles:

Author(s): P. Geetha, M. Kousalya, S. Geetha Lakshmi, R. Gopi.

DOI: 10.5958/0974-360X.2016.00046.9         Access: Open Access Read More

Author(s): J. Rubika

DOI: Not Available         Access: Open Access Read More

Author(s): M U Uhumwangho, K Latha, S A Sunil, M V Srikanth, K V Ramana Murthy

DOI: Not Available         Access: Open Access Read More

Author(s): Rituraj Singh Chundawat, Y.S. Sarangdevot, R.P.S. Rathore, Dharmendra Singh Sisodiya, Udaibhan Singh Rathore

DOI:         Access: Open Access Read More

Author(s): Siddharth Kumar Sahu, Ajazuddin, Tripti Banjare, Swapnil Gupta, Akansha Bhandarkar, Hemlata Sahu, Shradha Devi Diwedi, Pankaj Sahu, Palak Agrawal, Pooja Yadav, Aditi Bhatt, Kailash Sahu, Deeksha Dewangan, HemlataThapa, Deepika, GyaneshSahu, Mukesh Sharma, D. K. Tripathi, Amit Alexander

DOI: 10.5958/0974-360X.2018.00209.3         Access: Open Access Read More

Author(s): Suralkar Anupama A., Jadhav Asha S., Vaidya Gayatri S., Sharma Ashish, Meghraj Chaudary, Vivek Bhora

DOI: Not Available         Access: Open Access Read More

Author(s): Ram S Sakhare, Ashish B Roge, RL Bakal, MA Channawar, AV Chandewar

DOI: Not Available         Access: Open Access Read More

Author(s): B. Valli , S. Anand

DOI: 10.5958/0974-360X.2015.00179.1         Access: Open Access Read More

Author(s): Preeti K. Suresh, Abhishek K. Sah, Sanjay J. Daharwal

DOI: Not Available         Access: Open Access Read More

Author(s): Monisha N.

DOI: Not Available         Access: Open Access Read More

Author(s): Naveen MR, Santhosh YL

DOI: Not Available         Access: Open Access Read More

Author(s): Shashi Singh, Swati R. Dhande, Sneha M. Aggarwal, Avinash Suryawanshi, Vilasrao Kadam

DOI: Not Available         Access: Open Access Read More

Author(s): Som K. Madhvi, Manik Sharma, Javaid Iqbal, Mohd Younis

DOI: 10.5958/0974-360X.2019.00785.6         Access: Open Access Read More

Author(s): Gayathri. M

DOI: 10.5958/0974-360X.2015.00194.8         Access: Open Access Read More

Author(s): Vibhor K. Jain, Dheeraj Ahirwar, Bindu Jain, Bharati Ahirwar

DOI: 10.5958/0974-360X.2018.00120.8         Access: Open Access Read More

Author(s): Dayanand Reddy G, Bernard Mefi M, Bharathy H, Narasimha Kumar GV, Chitikela P Pullaiah, Ganesan R, Sathiya Rajeswaran P

DOI: 10.5958/0974-360X.2018.00622.4         Access: Open Access Read More

Author(s): S. Lakshmi kanthamma, Joyita Kriszhnamurthi, C. N. Hemalatha, M. Vijey Aanandhi

DOI: 10.5958/0974-360X.2018.00283.4         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags