Author(s): Sisira Padavala, Gopinath P

Email(s): Email ID Not Available

DOI: 10.5958/0974-360X.2016.00281.X   

Address: Sisira Padavala1, Dr. Gopinath P2
1BDS 2nd year, Saveetha Dental College, Saveetha University, Chennai.
2 Senior Lecturer, Department of Microbiology, Saveetha Dental College, Saveetha University, Chennai.
*Corresponding Author

Published In:   Volume - 9,      Issue - 9,     Year - 2016


ABSTRACT:
Capsular polysaccharides (K antigens) are one of the main virulence factors for Escherichia coli strains to cause urinary tract infections and neonatal meningitis. There are 50 chemically different capsular K antigens found, wherein only a few are associated with infective E.coli strains. These polysaccharides associated with disease that encodeK1 antigen (polysialic acid) are involved in causing a wide variety of infections such as septicemia, urinary tract infections, and meningitis. A total of 20 clinical isolates of E. coli were screened for the presence of neuC gene by PCR. We have observed 15% positivity among our isolates. This indicates that, the pathogenicity of urinary tract infections by these pathogens might be crucially played by this gene encoding K capsular polysaccharide.


Cite this article:
Sisira Padavala, Gopinath P. Detection of neuC gene for the presence of capsular polysaccharide among the clinical isolates of Escherichia coli. Research J. Pharm. and Tech 2016; 9(9):1454-1456. doi: 10.5958/0974-360X.2016.00281.X


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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