Author(s):
Sasikumar. C, Naveen Kumar.V, Mohana. S.J, Yasodha. S
Email(s):
sasikumarc@jeppiaarinstitute.org
DOI:
10.5958/0974-360X.2016.00198.0
Address:
Sasikumar. C1, Naveen Kumar.V2, Mohana. S.J3, Yasodha. S4
1Asst. Professor, Jeppiaar Institute of Technology, Sriperumbudur India
2Clinical Research Coordinator, Apollo Research and Innovations, Chennai, India
3PhD Research Scholar, Gurunank College, Chennai, India
4Research Scientist, Royal Bio Research Center, Chennai.India
*Corresponding Author
Published In:
Volume - 9,
Issue - 8,
Year - 2016
ABSTRACT:
In the present work evaluation of improved Antagonistic bacterial activity of antibiotic Meropenem with silver Nanodriblets, against Listeria monocytogens was studied. Respective Nanodriblets and nanoconjugates were amalgamated by chemical lessening method and synthesized Nanodriblets and nanoconjugates were categorized by UV-Vis spectroscopy, electron microscopy, Fourier Transform Infrared Spectroscopy (FT-IR) and Energy-dispersive X-ray spectroscopy (EDX). The synthesized Driblets were loaded into the respective antibiotics and the nanoformulated antibiotics were further characterized and showed 60 to 100 fold increase of antagonistic bacterial activity against the tested bacteria. Least minimal inhibitory concentration was also recorded in nanoformulated antibiotics. This study suggest possible utilization of nanoformulated antibiotics as a novel therapeutic agents against pathogenic bacteria.
Cite this article:
Sasikumar. C, Naveen Kumar.V, Mohana. S.J, Yasodha. S. Enhanced Antagonistic Bacterial Activity of Meropenem with Bioattuned Nanodriblet against Listeria monocytogeneses. Research J. Pharm. and Tech 2016; 9(8):1043-1054. doi: 10.5958/0974-360X.2016.00198.0
Cite(Electronic):
Sasikumar. C, Naveen Kumar.V, Mohana. S.J, Yasodha. S. Enhanced Antagonistic Bacterial Activity of Meropenem with Bioattuned Nanodriblet against Listeria monocytogeneses. Research J. Pharm. and Tech 2016; 9(8):1043-1054. doi: 10.5958/0974-360X.2016.00198.0 Available on: https://rjptonline.org/AbstractView.aspx?PID=2016-9-8-7