Author(s): K. Vijayakumar, A. Vijaya Anand

Email(s): vijaykanna1211@gmail.com

DOI: 10.5958/0974-360X.2016.00220.1   

Address: K. Vijayakumar1*, A. Vijaya Anand2
1Assistant Professor and Head, Department of Biochemistry, M.I.E.T. Arts and Science College, Trichirappalli-620 007, Tamil Nadu, India.
2Associate Professor and Head, Department of Human Genetics and Molecular Biology, Bharathiar University,Coimbatore-641046, Tamil Nadu, India.
*Corresponding Author

Published In:   Volume - 9,      Issue - 8,     Year - 2016


ABSTRACT:
The current study was carried out to evaluate the protective effect of P. guajava and its isolated fraction on CCl4 induced oxidative stress. Silymarin used as a standard drug for this study. The abnormalities of lipid peroxidative markers, enzymatic and non enzymatic antioxidants were assessed in both plasma and liver tissue. The values of thiobarbituric acid reactive substances (TBARS), lipid peroxides (LPO) and conjugated dienes (CDs) were increased, the values of enzymatic antioxidants includes super oxide dismutase (SOD), catalase (CAT), Glutathione peroxides (GPx) and non enzymatic antioxidants includes vitamin C, Vitamin E and reduced glutathione (GSH) were decreased in CCl4 induced rats. The treatment of P. guajava (100, 200 and 300 mg/kg, bw) and isolated fraction (20 mg/kg, bw) doses decreased the elevated levels of all these parameters and restored significantly. From this study, it can be concluded that the ethanolic leaf extract of P. guajava and its isolated fraction showed significant antioxidative action in CCl4 induced oxidative stress.


Cite this article:
K. Vijayakumar, A. Vijaya Anand. Protective Effects of Psidium guajava and its Isolated Fraction on CCl4 Induced Oxidative Stress. Research J. Pharm. and Tech 2016; 9(8):1155-1160. doi: 10.5958/0974-360X.2016.00220.1

Cite(Electronic):
K. Vijayakumar, A. Vijaya Anand. Protective Effects of Psidium guajava and its Isolated Fraction on CCl4 Induced Oxidative Stress. Research J. Pharm. and Tech 2016; 9(8):1155-1160. doi: 10.5958/0974-360X.2016.00220.1   Available on: https://rjptonline.org/AbstractView.aspx?PID=2016-9-8-29


Recomonded Articles:

Author(s): Nimbalkar V.V., Pansare P.M., Nishane B.B.

DOI: 10.5958/0974-360X.2015.00310.8         Access: Open Access Read More

Author(s): R. Manikandan, A. Vijaya Anand

DOI: 10.5958/0974-360X.2015.00056.6         Access: Open Access Read More

Author(s): R. Suresh, D. Benitojohnson, C. Maheswari, R. Venkatnarayanan, R.Manavalan

DOI: 10.5958/0974-360X.2017.00128.7         Access: Open Access Read More

Author(s): Karanje Abhijit Sampatrao, Kandale Jitendra Bhalchandra, Jadhav Ravindra, Patil Manohar

DOI: Not Available         Access: Open Access Read More

Author(s): Jitendra Patel, A. Venkateshwar Reddy, G.S. Kumar, D. Satyasai4 B. Bajari, V. Nagarjuna

DOI: 10.5958/0974-360X.2017.00232.3         Access: Open Access Read More

Author(s): K. Hemalatha, K. Priya Darsini, D. Sunitha

DOI: Not Available         Access: Open Access Read More

Author(s): Pradeep Kumar Samal

DOI: Not Available         Access: Open Access Read More

Author(s): Dayanand Reddy G, Bernard Mefi M, Bharathy H, Narasimha Kumar GV, Chitikela P Pullaiah, Ganesan R, Sathiya Rajeswaran P

DOI: 10.5958/0974-360X.2018.00622.4         Access: Open Access Read More

Author(s): Fahad Khalid Aldhafiri, Balakrishnan Santhanaraj, Gokulan Selvam, Khader Syed Zameer Ahamed, Ramasamy Subbaiya, Suriya Kumaresan, Ponnusamy Ponmurugan.

DOI: 10.5958/0974-360X.2017.00024.5         Access: Open Access Read More

Author(s): Sandeep Kataria1*, Dilsher Kaur2, Shaival Kamalaksha Rao3, Neha Sharma4, Ravi K Khajuria4

DOI: Not Available         Access: Open Access Read More

Author(s): K. Hemalatha*, K. Priya Darsini and D. Sunitha

DOI: Not Available         Access: Open Access Read More

Author(s): Radhey Shyam Kuamwat, K. Mruthunjaya, Manish Kumar Gupta

DOI: Not Available         Access: Open Access Read More

Author(s): CS Kandasamy, Mohammed Basil E, Shimna Thasnim PS, R Siva Kumar, V Gopal, R Venkatnarayanan

DOI: Not Available         Access: Open Access Read More

Author(s): Adryan Fristiohady, Wahyuni Wahyuni, Muhammad Ilyas Yusuf, Fadhliyah Malik, La Ode Muhammad Julian Purnama, Mentarry Bafadal, Mesi Leorita, Asriullah Jabar, Muhammad Hajrul Malaka, I Sahidin

DOI: 10.5958/0974-360X.2020.00807.0         Access: Open Access Read More

Author(s): S. S. Sheeba Tabassum, C. Rajaram1, S. Nelson Kumar, R. Manohar, K. Ravindra Reddy

DOI: 10.5958/0974-360X.2020.00101.8         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags