Author(s): Ashna A, Jeena S, Vidhya PV, Venkateswaramurthy. N, Sambathkumar. R

Email(s): venkateswaramurthy.n@jkkn.org

DOI: 10.5958/0974-360X.2016.00187.6   

Address: Ashna A, Jeena S, Vidhya PV, Venkateswaramurthy. N*, Sambathkumar. R
J.K.K. Nattraja College of Pharmacy, Kumarapalyam, Tamil Nadu, India
*Corresponding Author

Published In:   Volume - 9,      Issue - 7,     Year - 2016


ABSTRACT:
Statins are most effective in reducing the plasma cholesterol level by inhibiting hydroxyl methyl glutaryl coenzyme A reductase. Emerging evidence suggest that statins exert other mechanism of action called Pleiotropic effects; which are plaque stability, endothelial function modification, thrombus formation etc. Therefore therapeutic potential of statins extends beyond lipid lowering. Correctly underlying these pleiotropic effect suggest a new method to prevent and treat wide variety of life threatening disorders. Thus statins has added a wide scope of potential targets ranging from acute coronary syndrome to other renal infections and neuroleptic disorders.


Cite this article:
Ashna A, Jeena S, Vidhya PV, Venkateswaramurthy. N, Sambathkumar. R. Statins: Pleiotropic Effect. Research J. Pharm. and Tech. 2016; 9(7):977-981. doi: 10.5958/0974-360X.2016.00187.6


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DOI: 10.5958/0974-360X.2016.00187.6         Access: Open Access Read More

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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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