Praveen D, Ranadheer Chowdary P, Gandikota Thanmayi, Gangabathina Poojitha, Vijey Aanandhi M
Praveen D1*, Ranadheer Chowdary P1, Gandikota Thanmayi1, Gangabathina Poojitha1,
Vijey Aanandhi M2
1Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels University, Chennai, India
2Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Vels University, Chennai, India
Volume - 9,
Issue - 3,
Year - 2016
Background: Traditional Indian medicine has always found its way for the treatment of multiple diseases and conditions. Artocarpus heterophyllus is a common plant and can easily be exploited for its rich medical heritage.
Methods: Two leaf extracts were made. Both the aqueous and ethanolic extracts were subjected to phytochemical screening. Analgesic property was established with the help of Eddys hot plate ,acetic acid induced writhing ,Tail Flick methods. One way ANOVA was used to correlate the significance p<0.005. Antioxidant properties were evaluated with DPPH and Nitric oxide scavenging activity.
Results: The ethanolic extract shows a statistically significant (p<0.005) correlation towards the analgesic activity in both the methods namely hot plate method and writhing method. The ethanolic leaf extracts showed the following phytochemicals—Flavonoids, phenols, terpenoids, saponins, steroids while the aqueous extracts showed the presence of flavonoids, phenols, saponins and steroids. Both the extracts showed significant antioxidant activity.
Conclusion: This study shows the Phytochemical evaluation and analgesic activities of both the extracts. Hence further studies should be made to isolate the necessary constituent for both the activities.
Cite this article:
Praveen D, Ranadheer Chowdary P, Gandikota Thanmayi, Gangabathina Poojitha, Vijey Aanandhi M. Antioxidant and Analgesic Activity of Leaf Extracts of Artocarpus heterophyllus. Research J. Pharm. and Tech. 9(3): Mar., 2016; Page 257-261. doi: 0.5958/0974-360X.2016.00047.0