Author(s): Sahil Choudhari, A. Jothipriya

Email(s): choudharisahil@gmail.com ,

DOI: 10.5958/0974-360X.2016.00360.7   

Address: Sahil Choudhari1, Mrs. A. Jothipriya2
1I BDS, Department of Physiology, Saveetha Dental College, Chennai – 600 077
2Lecturer, Department of Physiology, Saveetha Dental College, Chennai – 600 077
Corresponding Author

Published In:   Volume - 9,      Issue - 10,     Year - 2016


ABSTRACT:
Non-alcoholic fatty liver disease (NAFLD) is an increasingly prevalent condition affecting adults and children, leading to significant morbidity. It is often associated with the metabolic syndrome, although multiple pathogenetic mechanisms have been suggested. In the coming decades, it promises to be the leading cause of liver disease in industrial countries. Clinic opathologically, it represents a wide spectrum of histologic abnormalities and clinical outcomes, ranging from benign hepatic steatosis to cirrhosis. Pathophysiologically, insulin resistance is thought to be pivotal in the development of steatosis, after which a second oxidative stressor produces lipid peroxidation and nonalcoholic steatohepatitis (NASH). Liver biopsy is the gold standard for diagnosis and prognosis. The need for an effective treatment is both clear and urgent, yet in the absence of proven therapies, treatment is directed toward weight loss and comorbidity management.


Cite this article:
Sahil Choudhari, A. Jothipriya. Non-Alcoholic Fatty Liver Disease . Research J. Pharm. and Tech 2016; 9(10):1782-1785. doi: 10.5958/0974-360X.2016.00360.7


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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