Author(s): Sandra Sagar, Gopinath P

Email(s): Email ID Not Available

DOI: 10.5958/0974-360X.2016.00315.2   

Address: Sandra Sagar1, Dr.Gopinath P2
1BDS 2nd Year, Saveetha Dental College, Saveetha University, Chennai
2Senior Lecturer, Department Of Microbiology, Saveetha Dental College, Saveetha University, Chennai
Corresponding Author

Published In:   Volume - 9,      Issue - 10,     Year - 2016

Widespread spread of CTX-M type extended-spectrum beta-lactamases (ESBL) in E. coli strains which are resistant to extended-spectrum cephalosporins is the most remarkable example for rapid and global spread of plasmid mediated antimicrobial resistance in bacteria. The incessant spread and global prevalence of ESBL resistance poses a serious threat to the human health, as it is responsible for the narrowing of therapeutic options pertaining to infections. A sum of 20 uropathogenic isolates of E. coli were subjected for the antibiotic susceptibility pattern using different antibiotics and followed by the detection of bla CTX-M gene by PCR. By which, we found increased percentage of isolates were resistant to different antibiotics and 30% of them were having this gene. This indicates the prevalence of such antibiotic resistance gene in our region. Proper antibiotic policies would promote the patients health condition better.

Cite this article:
Sandra Sagar, Gopinath P. Detection of bla CTX-M gene for ESBL Production Among Clinical Isolates of Escherichia coli. Research J. Pharm. and Tech 2016; 9(10):1593-1595. doi: 10.5958/0974-360X.2016.00315.2

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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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