Author(s): Jobin Jose, R Narayana Charyulu, Prashant Nayak

Email(s): jjmattam07@rediffmail.com

DOI: DOI: 10.5958/0974-360X.2016.00004.4   

Address: Jobin Jose*, R Narayana Charyulu, Prashant Nayak
Department of Pharmaceutics, NGSM Institute of Pharmaceutical Sciences, Paneer, Mangalore-575018, Karnataka, India
*Corresponding Author

Published In:   Volume - 9,      Issue - 1,     Year - 2016


ABSTRACT:
PAMAM dendrimer offers an ideal carrier for drug delivery that has the capacity to attach and discharge drugs by numerous ways. In this research work, we explored the potential of polyamidoamine dendrimers (PAMAM) as a carrier for ketoconazole and in vitro evaluation of ketoconazole- PAMAM complexes. Cytotoxicity studies were carried in J774A, mouse macrophage cell lines. Our research work revealed that binding of drug into dendrimers led to sustained release of ketoconazole in vitro. Results of the cytotoxicity studies also showed that the complexation of drugs with PAMAM dendrimer leads to the reduction in cytotoxicity of drugs.


Cite this article:
Jobin Jose, R Narayana Charyulu, Prashant Nayak. In Vitro Cytotoxicity Studies of Pamam Dendrimer with an Antifungal Agent. Research J. Pharm. and Tech. 9(1): Jan., 2016; Page 17-19. doi: DOI: 10.5958/0974-360X.2016.00004.4


Recomonded Articles:

Author(s): Arvindganth. R, Anupriya K.V., Kathiravan. G

DOI: 10.5958/0974-360X.2017.00105.6         Access: Open Access Read More

Author(s): Sangeeta S. Tanavade, Smt. Nilofer Naikwade, Dhanyakumar D. Chougule

DOI: Not Available         Access: Open Access Read More

Author(s): Deepak H B, Sabina Evan Prince

DOI: 10.5958/0974-360X.2017.00491.7         Access: Open Access Read More

Author(s): S. Krishnakumar, R. Divya, N.R. Kanchana Devi, G. Keerthana, A. Ancy Judi

DOI: 10.5958/0974-360X.2017.00234.7         Access: Open Access Read More

Author(s): C. M. Jamkhandi, John Intru Disouza

DOI: Not Available         Access: Open Access Read More

Author(s): Sumit Phulera, Neelam Gurung, Kavita Maria Arora, Gaurav Kumar, Loganathan Karthik, Kokati Venkata Bhaskara Rao

DOI: Not Available         Access: Open Access Read More

Author(s): Chinedu Fredrick Anowi, Nnabuife Chinedu Cardinal, A.F. Onyegbule, L.N. Anowi

DOI: Not Available         Access: Open Access Read More

Author(s): V. Gurumurthy, R. Deveswaran, S. Bharath, B.V. Basavaraj, V. Madhavan

DOI: Not Available         Access: Open Access Read More

Author(s): NasimunIslam N1., Jemimah Naine S., Shaik Jameel, S.S. Khora, Venkat Kumar, Mohanasrinivasan V., C. Subathra Devi, Panneerselvam A.

DOI: Not Available         Access: Open Access Read More

Author(s): C. M. Jamkhandi, John Intru Disouza

DOI: Not Available         Access: Open Access Read More

Author(s): Mukesh Kumar Singh, A. Prathapan, Kushagra Nagori, S. Ishwarya, K.G Raghu

DOI:         Access: Open Access Read More

Author(s): Sarika R. Deshmukh, Solomon Habtemariam, Prasad A. Wadegaonkar

DOI:         Access: Open Access Read More

Author(s): Nitin Kumar, Satyendra Singh, Manvi, Rajiv Gupta

DOI:         Access: Open Access Read More

Author(s): Merin Babu, Subin Varghese Thomas, Sruthi T P, Jipnomon Joseph

DOI: 10.5958/0974-360X.2019.00651.6         Access: Open Access Read More

Author(s): Imon Rahman, Md. Tanvir Kabir, Md. Nasiful Islam, Mushfiqa Muqaddim, Shahana Sharmin, Mohammed Sami Ullah, Md. Sahab Uddin

DOI: 10.5958/0974-360X.2019.00365.2         Access: Open Access Read More

Author(s): Amaq Fadholly, Arif N. M. Ansori, Shara Jayanti, Annise Proboningrat, Muhammad K. J. Kusala, Naimah Putri, Fedik A. Rantam, Sri A. Sudjarwo

DOI: 10.5958/0974-360X.2019.00591.2         Access: Open Access Read More

Author(s): S. Ramachandran, Vijey Aanandhi M, Binoy Varghese Cheriyan

DOI: 10.5958/0974-360X.2019.00684.X         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags