Author(s): Dinesh Kumar V., Priya Ranjan Prasad Verma

Email(s): thendral.din007@gmail.com

DOI: 10.5958/0974-360X.2015.00136.5   

Address: Dinesh Kumar V.*, Priya Ranjan Prasad Verma
Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, Jharkhand, India
*Corresponding Author

Published In:   Volume - 8,      Issue - 7,     Year - 2015


ABSTRACT:
Quercetin loaded Poly (e caprolactone; PCL) nanoparticles were prepared by the solvent displacement method. The influences of formulation variables (polymer and surfactant concentration) were investigated. The results of formulations F1-F9 showed Particle size (nm) in a different medium ranged from 189.10 ± 0.28 to 252.14 ± 2.32 in 0.1 N HCl and 184.06 ± 3.84 to 288.54 ± 2.86 in phosphate buffer pH 7.4, Dissolution efficiency (%) of 46.42 ± 5.42 to 72.20 ± 0.68 and drug loading (%) of 7.18 ± 0.25 to 9.27 ± 0.50. High Resolution-Transmission Electron Microscopy image represents the spherical and smooth surface of nanoparticles. The results suggested that, quercetin loaded polymeric nanoparticles may be the viable strategy for controlled release for more than 48 hours, and improves the physical stability of quercetin.


Cite this article:
Dinesh Kumar V., Priya Ranjan Prasad Verma. Development of a poly (ε Caprolactone) based nanoparticles for oral delivery of Quercetin. Research J. Pharm. and Tech. 8(7): July, 2015; Page 836-840. doi: 10.5958/0974-360X.2015.00136.5


Recomonded Articles:

Author(s): Vandana Gautam, Dhriti Kapoor, Saroj Arora, Renu Bhardwaj*

DOI: 10.5958/0974-360X.2016.00166.9         Access: Open Access Read More

Author(s): Malarkodi Velraj, P. Jasmine Shiney, Biplab Paul, Rashmi. S, Nivethitha

DOI: 10.5958/0974-360X.2017.00006.3         Access: Open Access Read More

Author(s): Arvindganth. R, Anupriya K.V., Kathiravan. G

DOI: 10.5958/0974-360X.2017.00105.6         Access: Open Access Read More

Author(s): Baviskar Anagha, Hiremath Shivanand, Akul Manoj, Pawar Poonam

DOI: Not Available         Access: Open Access Read More

Author(s): Hitesh Jain, Rushi Panchal, Dilrose Pabla, Jaimini Patel, Mansi Khirwadkar

DOI: Not Available         Access: Open Access Read More

Author(s): S. Krishnakumar, R. Divya, N.R. Kanchana Devi, G. Keerthana, A. Ancy Judi

DOI: 10.5958/0974-360X.2017.00234.7         Access: Open Access Read More

Author(s): Soumya Khare, Amit Alexander, Ajazuddin, Nisha Amit

DOI: Not Available         Access: Open Access Read More

Author(s): Annapurna Uppala, Naga Swapna V, Neelima Devi R, Glory Sheren G, Kishore Kumar B

DOI: 10.5958/0974-360X.2015.00230.9         Access: Open Access Read More

Author(s): B Chengaiah, M Alagusundaram, S Ramkanth, C Madhusudhana Chetty

DOI: Not Available         Access: Open Access Read More

Author(s): Sree Vidhya T.M., Geetha

DOI: Not Available         Access: Open Access Read More

Author(s): Surbhi Sharma1*, M.S. Ashawat2 and N.S. Solanki3

DOI: Not Available         Access: Open Access Read More

Author(s): Nurul Huda Md. Masu, Kaiser Hamid, Abu Hasanat Zulfiker, Kamal Hossain, Kaniz Fatima Urmi

DOI: Not Available         Access: Open Access Read More

Author(s): Perumal Andal, S. Tamilselvy, P. Indra Priyatharesini

DOI: 10.5958/0974-360X.2018.00509.7         Access: Open Access Read More

Author(s): Maytham M. Alabassi

DOI: 10.5958/0974-360X.2018.00758.8         Access: Open Access Read More

Author(s): Amaninder Kaur Riat, Denu geyi, Mohammed Rafi, Gulshandeep Kaur

DOI: 10.5958/0974-360X.2018.00908.3         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags