Author(s): Prabha Verma, Suresh Kumar Sutrakar

Email(s): sutrakar.skumar35@gmail.com

DOI: 10.5958/0974-360X.2015.00288.7   

Address: Dr. Prabha Verma1, Dr. Suresh Kumar Sutrakar2
1Lecturer & Head, Department of Biochemistry, M.L.B. Medical College, Jhansi (U.P) India-284001
2Associate Professor, Department of Pathology, S.S. Medical College and Asso. S.G.M. Hospital, Rewa (M.P.) India-486001
*Corresponding Author

Published In:   Volume - 8,      Issue - 12,     Year - 2015


ABSTRACT:
The dyslipidemic and antioxidant activity of Piper longum extract has been studied in triton and high fat diet fed hyperlipemic rats. The extract lowered the serum lipids at (200 mg/kg, b.w., p.o.) in triton WR-1339 induced hyperlipidemia. Chronic feeding of this extract (100 mg/kg, b.w.) in animals simultaneously fed with high fat diet (HFD) for 30 days caused lowering of lipid and apoproteins level of lipoproteins in experimental animals. P. langum activates lipolytic enzymes in plasma and liver lipids. These extract increased faecal bile acid extraction and enhanced plasma lecithin: cholesterol acyltransferase activity. Piper langum extract showed potent inhibition of antioxidant and scavenger of oxygen free radical activity (in vitro) and it induced oxidative stress.


Cite this article:
Prabha Verma, Suresh Kumar Sutrakar. Dyslipidemic and Antioxidant activity of Piper longum extract in hyperlipemic rats. Research J. Pharm. and Tech. 8(12): Dec., 2015; Page 1609-1614. doi: 10.5958/0974-360X.2015.00288.7


Recomonded Articles:

Author(s): U.S Mahadeva Rao, Khamsah Suryati Mohd, Abdurrazaq Muhammad, Bashir Ado Ahmad, Mohaslinda Mohamad, Rosmawati Mat Ali

DOI: Not Available         Access: Open Access Read More

Author(s): Vandana Gautam, Dhriti Kapoor, Saroj Arora, Renu Bhardwaj*

DOI: 10.5958/0974-360X.2016.00166.9         Access: Open Access Read More

Author(s): A. Julius, Ramachandran Vedasendiyar, Archana Devakannan, Sujatha Rajaraman, Balamurugan Rangasamy, V. Saravanan

DOI: 10.5958/0974-360X.2017.00062.2         Access: Open Access Read More

Author(s): Deepak Karki, Gururaj S. Kulkarni, Shivakumar Swamy, Sheeba FR

DOI: 10.5958/0974-360X.2017.00750.8         Access: Open Access Read More

Author(s): Praveen D, Ranadheer Chowdary P, Gandikota Thanmayi, Gangabathina Poojitha, Vijey Aanandhi M

DOI: 0.5958/0974-360X.2016.00047.0         Access: Open Access Read More

Author(s): Rekha Rajendran, R Hemachander, T Ezhilarasan, C Keerthana, DL Saroja, KV Saichand, Mohamed Gasim Abdullah

DOI: Not Available         Access: Open Access Read More

Author(s): R. Suresh, D. Benitojohnson, C. Maheswari, R. Venkatnarayanan, R.Manavalan

DOI: 10.5958/0974-360X.2017.00128.7         Access: Open Access Read More

Author(s): Krishnendu Acharya*, Somanjana Khatua, Salman Sahid

DOI: Not Available         Access: Open Access Read More

Author(s): Karanje Abhijit Sampatrao, Kandale Jitendra Bhalchandra, Jadhav Ravindra, Patil Manohar

DOI: Not Available         Access: Open Access Read More

Author(s): J.S. Vaghela, S.S. Sisodia

DOI: Not Available         Access: Open Access Read More

Author(s): Tarasankar Maity, Ayaz Ahmad, Nilanjan Pahari, Subarna Ganguli

DOI: Not Available         Access: Open Access Read More

Author(s): Subin Mary Zachariah, N. Aleykutty, Vidya Viswanad, Halima O.A.

DOI: Not Available         Access: Open Access Read More

Author(s): Das Biswajit, Dash Suvakanta, Choudhury Ramesh Chandra

DOI: Not Available         Access: Open Access Read More

Author(s): U.S MahadevaRao, Khamsah Suryati Mohd, Siti Zulaikha Bt Abd Halim, Masitah Bt Khamis

DOI: Not Available         Access: Open Access Read More

Author(s): Anuradha A. Ranpise, Shilpa P. Chaudhari, Atul A. Phatak, Pratiksha M. Kadam

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags