Author(s): Abdullahi Rabiu Abubakar, Nordin Bin Simbak, Mainul Haque

Email(s): runurono@gmail.com

DOI: Not Available

Address: Abdullahi Rabiu Abubakar1, Nordin Bin Simbak2, Mainul Haque3*
1Masters Student, Unit of Pharmacology, Faculty of Medicine and Health Sciences (FPSK), Universiti Sultan Zainal Abidin (UniSZA), 20400 Kuala Terengganu, Terengganu, Malaysia
2Professor and Dean, FPSK, UniSZA, 20400, Kuala Terengganu, Malaysia
3Professor, Head of the Unit of Pharmacology, FPSK, UniSZA, 20400 Kuala Terengganu, Terengganu, Malaysia.
*Corresponding Author

Published In:   Volume - 7,      Issue - 9,     Year - 2014


ABSTRACT:
Many factors predispose patient to develop adverse drug reactions (ADRs), some of these factors are drug related, patient related, disease related, social and adverse drug related. The contributions of these factors to development of ADRs are very crucial and are well documented in medical literature. It has become necessary for every medical practitioner to consider these factors in order to prescribe the best medication to his patients. The current classification of ADRs is only based on drug known pharmacology and dose dependent of its action. In order to give comprehensive classification, the time course of its appearance and its severity as well as patient susceptibility are taken into consideration. Knowledge of causality assessment enables the medical practitioners to clarify the likelihood that the suspected adverse drug reaction is actually due to the medicine. This requires careful patient monitoring because adverse drug reaction can be difficult and a times impossible to distinguish from patient disease condition. The purpose of this article is to review the factors affecting the development of ADRs, its broader classification and to assess causal relationship between the suspected drug and appearance of ADRs.


Cite this article:
Abdullahi Rabiu Abubakar, Nordin Bin Simbak, Mainul Haque. Adverse Drug Reactions: Predisposing Factors, Modern Classifications and Causality Assessment. Research J. Pharm. and Tech. 7(9): Sept. 2014 Page 1091-1098.


Recomonded Articles:

Author(s): Meenakshi K, Safa M, Karthick T, Sivaranjani N

DOI: 10.5958/0974-360X.2017.00253.0         Access: Open Access Read More

Author(s): Divyadharsini V, Jayanth Kumar V

DOI: 10.5958/0974-360X.2019.00048.9         Access: Closed Access Read More

Author(s): K. Gnanaprakash, K.B. Chandhra Shekhar, C. Madhu Sudhana Chetty

DOI: Not Available         Access: Open Access Read More

Author(s): Mahadeva Rao U.S., Suganya M. Utharkar, C. Shanmuga Sundaram

DOI: 10.5958/0974-360X.2015.00307.8         Access: Open Access Read More

Author(s): Deepak H B, Sabina Evan Prince

DOI: 10.5958/0974-360X.2017.00491.7         Access: Open Access Read More

Author(s): R. Pandian , Lalitha Kumari

DOI: 10.5958/0974-360X.2016.00471.6         Access: Open Access Read More

Author(s): Loveleen Preet Kaur, Rajeev Garg, GD Gupta

DOI: Not Available         Access: Open Access Read More

Author(s): Ashika Rachael Samuel, Giffrina Jeyaraj

DOI: 10.5958/0974-360X.2015.00210.3         Access: Open Access Read More

Author(s): A Pavan Kumar, J Satyanaryana, V Sai Kishore, TE Gopala Krishna Murthy

DOI: Not Available         Access: Open Access Read More

Author(s): Sonali Kashyap, Shikhar Bajaj, Jabanjalin Hida

DOI: 10.5958/0974-360X.2017.00362.6         Access: Open Access Read More

Author(s): Dhananjay Sangle, Amit Naik, Amol Ghorpade, Vikram Ghatkar, Suvarna Ghuge, Dipti Ingle, Rishikesh Ingle

DOI: Not Available         Access: Open Access Read More

Author(s): P. Grace Kanmani Prince, Rani Hemamalini, U. Anitha, J. Premalatha, K. Sudheera

DOI: 10.5958/0974-360X.2017.00613.8         Access: Open Access Read More

Author(s): Asija Rajesh, Patel Pinkesh, Asija Sangeeta

DOI: Not Available         Access: Open Access Read More

Author(s): Jayawardhani V., Rajesh A. Kamtane, Ashok K. Kulkarni

DOI: Not Available         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags