Alpesh B. Limbasiya, Pankaj P. Kapupara, Ketan V. Shah
Alpesh B. Limbasiya*, Pankaj P. Kapupara, Ketan V. Shah
Department of Quality Assurance, School of Pharmacy, RK University, Rajkot-360 020, Gujarat, India
Volume - 7,
Issue - 6,
Year - 2014
Novel, simple, sensitive, rapid, accurate and economical spectrophotometric method has been developed for simultaneous estimation of Serratiopeptidase (SER) and Diclofenac potassium (DCL). This method involves solving of simultaneous equations based on measurement of absorbances at two wavelengths 230 nm and 276 nm. Both the drugs obey the Beer’s law in the concentration ranges of 2-40 µg/ml and 1-70 µg/ml for Serratiopeptidase and Diclofenac potassium respectively. The regression coefficient (r2) values were found to be 0.9995 for SER and 0.9999 for DCL. Result of the method was validated statistically and by recovery studies.
Cite this article:
Alpesh B. Limbasiya, Pankaj P. Kapupara, Ketan V. Shah. Development and Validation of Analytical Method for Simultaneous Estimation of Diclofenac potassium and Serratiopeptidase in Pharmaceutical Formulation. Research J. Pharm. and Tech. 7(6): June, 2014; Page 655-659.