An antioxidant is a molecule that inhibits the oxidation of other molecules. Antioxidants plays a major role in maintanence of health and prevention of disease. free radicals and antioxidants are widely discussed in the clinical and nutritional literature. Antioxidants are needed to prevent the formation and oppose the actions of reactive oxygen and nitrogen species, which are generated in vivo and cause damage to DNA, lipids, proteins, and other biomolecules. Many dietary compounds have been suggested to be important antioxidants: The evidence for a key role of vitamins E and C is strong, but that for carotenoids and related plant pigments is weaker. Interest is also growing in the role of plant phenolics, especially flavonoids. Some antioxidants can exert prooxidant effects in vitro, but their physiological relevance is uncertainFree radical production occurs continuously in all cells as part of normal cellular function. However, excess free radical production originating from endogenous or exogenous sources might play a role in many diseases. Antioxidants prevent free radical induced tissue damage by preventing the formation of radicals, scavenging them, or by promoting their decomposition. This short review discuss the details about the role of antioxidants as enzymatic and non enzymaticanti oxidants with its application and it's disorders.
Cite this article:
M. Vaishali. Antioxidants in Health and Diseases. Research J. Pharm. and Tech. 7(4): April, 2014; Page 489-493.