Author(s):
Jahanzeb Khan, Muhammad Asad Saeed, Saad Touqeer, Sharjeel Adnan, Zeeshan Masood, Muhammad Zaman
Email(s):
zaib_zaib94@yahoo.com
DOI:
Not Available
Address:
Jahanzeb Khan*, Muhammad Asad Saeed, Saad Touqeer, Sharjeel Adnan, Zeeshan Masood, Muhammad Zaman
Department of Pharmacy, The University of Lahore, Lahore, Pakistan.
*Corresponding Author
Published In:
Volume - 7,
Issue - 2,
Year - 2014
ABSTRACT:
Antihyperglycemic, hypoglycemic and cytotoxic activities of methanolic extract of Albizia lebbeck and Trigonella corniculata were studied. Hypoglycemic action of plants was investigated using normoglycemic rabbits (acute study only), whereas antihyperglycemic activity was studied using alloxan induced diabetic rabbits (acute and chronic study). Results revealed both plant extracts and their mixture having significant anti diabetic potential at dose of 200mg/kg comparable to standard drug Glibenclamide (0.5 mg/kg). Brine shrimp assay was used for the determination of cytotoxicity and results showed plants to have low toxic potential (LD50>1000 microgram). The study conducted proves both plants and their mixture to have high potential for the treatment of diabetes.
Cite this article:
Jahanzeb Khan, Muhammad Asad Saeed, Saad Touqeer, Sharjeel Adnan, Zeeshan Masood, Muhammad Zaman. Antihyperglycemic, Hypoglycemic and Cytotoxic Activity of Albizia lebbek and Trigonella corniculata. Research J. Pharm. and Tech. 7(2): Feb. 2014; Page 191-195.
Cite(Electronic):
Jahanzeb Khan, Muhammad Asad Saeed, Saad Touqeer, Sharjeel Adnan, Zeeshan Masood, Muhammad Zaman. Antihyperglycemic, Hypoglycemic and Cytotoxic Activity of Albizia lebbek and Trigonella corniculata. Research J. Pharm. and Tech. 7(2): Feb. 2014; Page 191-195. Available on: https://rjptonline.org/AbstractView.aspx?PID=2014-7-2-6